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Lin37 Gene Detail
Summary
  • Symbol
    Lin37
  • Name
    lin-37 DREAM MuvB core complex component
  • Synonyms
    1810054G18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922910
    NCBI Gene: 75660
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:30254866-30259263 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 18.58 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    237 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922910
 protein coding gene Chr7:30254866-30259289 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032027
 protein coding gene Chr7:29560476-29564873 (-)
A/J MGP_AJ_G0032004
 protein coding gene Chr7:28760371-28764768 (-)
AKR/J MGP_AKRJ_G0031937
 protein coding gene Chr7:29492091-29496488 (-)
BALB/cJ MGP_BALBcJ_G0032011
 protein coding gene Chr7:28941878-28946275 (-)
C3H/HeJ MGP_C3HHeJ_G0031730
 protein coding gene Chr7:29948305-29952702 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032477
 protein coding gene Chr7:30518326-30529096 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029527
 protein coding gene Chr7:29787696-29792313 (-)
CAST/EiJ MGP_CASTEiJ_G0031064
 protein coding gene Chr7:23203765-23208145 (-)
CBA/J MGP_CBAJ_G0031696
 protein coding gene Chr7:31971944-31976341 (-)
DBA/2J MGP_DBA2J_G0031848
 protein coding gene Chr7:28489258-28493638 (-)
FVB/NJ MGP_FVBNJ_G0031805
 protein coding gene Chr7:28620445-28624842 (-)
LP/J MGP_LPJ_G0031929
 protein coding gene Chr7:29870388-29874768 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031841
 protein coding gene Chr7:31213411-31217808 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032505
 protein coding gene Chr7:29001519-29005915 (-)
PWK/PhJ MGP_PWKPhJ_G0027017
 protein coding gene Chr4:37010386-37016532 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030623
 protein coding gene Chr7:20010906-20015283 (-)
WSB/EiJ MGP_WSBEiJ_G0031174
 protein coding gene Chr7:29387768-29392451 (-)



Homology
more
  • Human Ortholog
    LIN37, lin-37 DREAM MuvB core complex component
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LIN37, lin-37 DREAM MuvB core complex component
  • Synonyms
    F25965, lin-37, ZK418.4
  • Links
    NCBI Gene ID: 55957
    neXtProt AC: NX_Q96GY3
    UniProt: Q96GY3

  • Chr Location
    19q13.12; chr19:35748361-35754519 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    33
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036845 Ensembl Gene Model | MGI Sequence Detail 4398 C57BL/6J ±  kb
transcript ENSMUST00000043975 Ensembl | MGI Sequence Detail 998 Not Applicable  
polypeptide ENSMUSP00000048557 Ensembl | MGI Sequence Detail 246 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 33
    cDNA 33

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:247509 Mages CF, et al., The DREAM complex through its subunit Lin37 cooperates with Rb to initiate quiescence. Elife. 2017 Sep 18;6:e26876
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory