Cdyl2 MGI Mouse Gene Detail - MGI:1923046 - chromodomain protein, Y chromosome-like 2

Symbol

Cdyl2
Name

chromodomain protein, Y chromosome-like 2
Synonyms

1700029M19Rik, 4930453I21Rik

Feature Type

protein coding gene
IDs

MGI:1923046
NCBI Gene: 75796
Alliance

gene page
Transcription Start Sites

11 TSS

Sequence Map

Chr8:117301139-117459730 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 8, 63.15 cM, cytoband E1
Mapping Data

3 experiments

SNPs within 2kb

5200 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1923046	protein coding gene	Chr8:117295462-117459730 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0034164	protein coding gene	Chr8:119661795-119838219 (-)
A/J	MGP_AJ_G0034144	protein coding gene	Chr8:114801969-114967050 (-)
AKR/J	MGP_AKRJ_G0034071	protein coding gene	Chr8:118135449-118309619 (-)
BALB/cJ	MGP_BALBcJ_G0034138	protein coding gene	Chr8:114992378-115166529 (-)
C3H/HeJ	MGP_C3HHeJ_G0033849	protein coding gene	Chr8:118853340-119025026 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0034658	protein coding gene	Chr8:123726140-123906349 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0031600	protein coding gene	Chr8:107744191-107914082 (-)
CAST/EiJ	MGP_CASTEiJ_G0033176	protein coding gene	Chr8:118646578-118832502 (-)
CBA/J	MGP_CBAJ_G0033822	protein coding gene	Chr8:128162748-128357117 (-)
DBA/2J	MGP_DBA2J_G0033978	protein coding gene	Chr8:114025489-114195148 (-)
FVB/NJ	MGP_FVBNJ_G0033921	protein coding gene	Chr8:113012382-113177526 (-)
LP/J	MGP_LPJ_G0034067	protein coding gene	Chr8:119797914-119975541 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0033968	protein coding gene	Chr8:130806011-130988591 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0034676	protein coding gene	Chr8:118222942-118398696 (-)
PWK/PhJ	MGP_PWKPhJ_G0032878	protein coding gene	Chr8:113733167-113901655 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0032718	protein coding gene	Chr8:116901293-117095217 (-)
WSB/EiJ	MGP_WSBEiJ_G0033292	protein coding gene	Chr8:118927738-119106862 (-)

Human Ortholog

CDYL2, chromodomain Y like 2

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CDYL2, chromodomain Y like 2
Synonyms

PCCP1
Links

HGNC:23030

NCBI Gene ID: 124359

neXtProt AC: NX_Q8N8U2

UniProt: Q8N8U2
Chr Location

16q23.2; chr16:80597907-80805037 (-) GRCh38

MGI Vertebrate Homology

Cdyl2 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: CDYL2
Gene Tree

Cdyl2

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Phenotype Summary

5 phenotypes from 1 allele in 1 genetic background
14 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

72
Endonuclease-mediated

3
Gene trapped

69
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

86 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

4
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

27

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

38
RefSeq

4
UniProt

4
CCDS

CCDS40488.1

Ensembl

ENSMUSG00000031758 (Evidence)
NCBI Gene

75796

			Length	Strain/Species	Flank
genomic	ENSMUSG00000031758	Ensembl Gene Model \| MGI Sequence Detail	158592	C57BL/6J	± kb
transcript	ENSMUST00000109102	Ensembl \| MGI Sequence Detail	2411	Not Applicable
polypeptide	ENSMUSP00000104730	Ensembl \| MGI Sequence Detail	503	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000029351 chromodomain Y-like protein 2

(term hierarchy)
InterPro Domains

IPR000953 Chromo/chromo shadow domain

IPR023780 Chromo domain

IPR023779 Chromo domain, conserved site

IPR016197 Chromo-like domain superfamily

IPR029045 ClpP/crotonase-like domain superfamily

IPR014748 Enoyl-CoA hydratase, C-terminal

IPR001753 Enoyl-CoA hydratase/isomerase

IPR051053 Enoyl-CoA hydratase/isomerase and chromodomain-containing protein

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All nucleic 27

cDNA 27

Microarray probesets 3

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MGI:1917321

Summaries

All 34

Gene Ontology 2

Phenotypes 14
Earliest

J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Cdyl2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr83079	Chr8:117460062-117460093 (-)	-348 bp
Tssr83078	Chr8:117459994-117460053 (-)	-294 bp
Tssr83077	Chr8:117459800-117459815 (-)	-78 bp
Tssr83076	Chr8:117459566-117459638 (-)	128 bp
Tssr83075	Chr8:117440594-117440603 (-)	19,131 bp
Tssr83074	Chr8:117438206-117438249 (-)	21,502 bp
Tssr83073	Chr8:117434894-117434898 (-)	24,834 bp
Tssr83072	Chr8:117404692-117404706 (-)	55,031 bp
Tssr83071	Chr8:117404548-117404562 (-)	55,175 bp
Tssr83070	Chr8:117399899-117399925 (-)	59,818 bp
Tssr83069	Chr8:117343085-117343089 (-)	116,643 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24