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Fam227b Gene Detail
Summary
  • Symbol
    Fam227b
  • Name
    family with sequence similarity 227, member B
  • Synonyms
    4930525F21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923073
    NCBI Gene: 75823
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:125825403-125993924 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 61.76 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3219 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923073
 protein coding gene Chr2:125825403-125994048 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026436
 protein coding gene Chr2:129192323-129355680 (-)
A/J MGP_AJ_G0026399
 protein coding gene Chr2:123937120-124107991 (-)
AKR/J MGP_AKRJ_G0026375
 protein coding gene Chr2:127480743-127652261 (-)
BALB/cJ MGP_BALBcJ_G0026411
 protein coding gene Chr2:124223271-124387274 (-)
C3H/HeJ MGP_C3HHeJ_G0026155
 protein coding gene Chr2:127962865-128150426 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026857
 protein coding gene Chr2:133301925-133484800 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024234
 protein coding gene Chr2:118717141-118861677 (-)
CAST/EiJ MGP_CASTEiJ_G0025616
 protein coding gene Chr2:128218677-128383526 (-)
CBA/J MGP_CBAJ_G0026135
 protein coding gene Chr2:138145815-138354442 (-)
DBA/2J MGP_DBA2J_G0026269
 protein coding gene Chr2:123355572-123523868 (-)
FVB/NJ MGP_FVBNJ_G0026233
 protein coding gene Chr2:122029872-122190345 (-)
LP/J MGP_LPJ_G0026374
 protein coding gene Chr2:129421159-129596011 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026253
 protein coding gene Chr2:142242856-142432667 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026912
 protein coding gene Chr2:127510780-127690014 (-)
PWK/PhJ MGP_PWKPhJ_G0025352
 protein coding gene Chr2:122895634-123072567 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025154
 protein coding gene Chr2:126603305-126759082 (-)
WSB/EiJ MGP_WSBEiJ_G0025690
 protein coding gene Chr2:128412590-128585907 (-)



Homology
more
  • Human Ortholog
    FAM227B, family with sequence similarity 227 member B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM227B, family with sequence similarity 227 member B
  • Synonyms
    C15orf33
  • Links
    NCBI Gene ID: 196951
    neXtProt AC: NX_Q96M60
    UniProt: Q96M60

  • Chr Location
    15q21.2; chr15:49326962-49620929 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027209 Ensembl Gene Model | MGI Sequence Detail 168522 C57BL/6J ±  kb
    transcript ENSMUST00000110446 Ensembl | MGI Sequence Detail 1858 Not Applicable  
    polypeptide ENSMUSP00000106076 Ensembl | MGI Sequence Detail 532 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 2
    References
    more
    • Summaries
      All 26
      Phenotypes 10
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory