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Pramex1 Gene Detail
Summary
  • Symbol
    Pramex1
  • Name
    PRAME like, X-linked 1
  • Synonyms
    4930534P07Rik, Prame
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923079
    NCBI Gene: 75829
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:134513751-134528454 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 57.26 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    479 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923079
 protein coding gene ChrX:134513662-134528454 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036086
 protein coding gene ChrX:132954683-132974712 (-)
A/J MGP_AJ_G0036064
 protein coding gene ChrX:132334072-132349123 (-)
AKR/J MGP_AKRJ_G0035990
 protein coding gene ChrX:136580208-136604216 (-)
BALB/cJ MGP_BALBcJ_G0036054
 protein coding gene ChrX:130747820-130762953 (-)
C3H/HeJ MGP_C3HHeJ_G0035764
 protein coding gene ChrX:132923574-132937684 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036576
 protein coding gene ChrX:136744264-136759734 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033405
 protein coding gene ChrX:124394320-124408960 (-)
CAST/EiJ MGP_CASTEiJ_G0035051
 protein coding gene ChrX:113860874-113879314 (+)
CBA/J MGP_CBAJ_G0035738
 protein coding gene ChrX:140947787-140962841 (-)
DBA/2J MGP_DBA2J_G0035894
 protein coding gene ChrX:131685880-131703920 (-)
FVB/NJ MGP_FVBNJ_G0035831
 protein coding gene ChrX:130873822-130891615 (-)
LP/J MGP_LPJ_G0035987
 protein coding gene ChrX:133859105-133877301 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035865
 protein coding gene ChrX:148325333-148340323 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036612
 protein coding gene ChrX:132289897-132306244 (-)
PWK/PhJ MGP_PWKPhJ_G0034742
 protein coding gene ChrX:110772998-110787150 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034574
 protein coding gene ChrX:114490276-114505186 (-)
WSB/EiJ MGP_WSBEiJ_G0035184
 protein coding gene ChrX:130641304-130655975 (-)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000031411 Ensembl Gene Model | MGI Sequence Detail 14704 C57BL/6J ±  kb
    transcript ENSMUST00000113159 Ensembl | MGI Sequence Detail 2267 Not Applicable  
    polypeptide ENSMUSP00000108784 Ensembl | MGI Sequence Detail 462 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • InterPro Domains
      IPR032675 Leucine-rich repeat domain superfamily
      IPR050694 PRAME domain-containing protein
    Molecular
    Reagents
    less
    • All nucleic 2
      cDNA 2

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:6437226
    References
    more
    • Summaries
      All 25
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 1
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory