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Nupr2 Gene Detail
Summary
  • Symbol
    Nupr2
  • Name
    nuclear protein transcriptional regulator 2
  • Synonyms
    1810010E01Rik, 4930579G22Rik, Nupr1l
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923099
    NCBI Gene: 69034
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:129937381-129942629 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 68.26 cM, cytoband F
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    292 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923099
 protein coding gene Chr5:129937381-129942630 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030135
 protein coding gene Chr5:134011784-134018136 (+)
A/J MGP_AJ_G0030103
 protein coding gene Chr5:128355048-128360361 (+)
AKR/J MGP_AKRJ_G0030036
 protein coding gene Chr5:132527699-132532793 (+)
BALB/cJ MGP_BALBcJ_G0030113
 protein coding gene Chr5:129706697-129712010 (+)
C3H/HeJ MGP_C3HHeJ_G0029829
 protein coding gene Chr5:133089305-133094554 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030566
 protein coding gene Chr5:139137435-139142713 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027791
 protein coding gene Chr5:122740367-122743083 (+)
CAST/EiJ MGP_CASTEiJ_G0029239
 protein coding gene Chr5:132395873-132401163 (+)
CBA/J MGP_CBAJ_G0029799
 protein coding gene Chr5:144562173-144570531 (+)
DBA/2J MGP_DBA2J_G0029950
 protein coding gene Chr5:128319934-128325183 (+)
FVB/NJ MGP_FVBNJ_G0029905
 protein coding gene Chr5:127417837-127423076 (+)
LP/J MGP_LPJ_G0030038
 protein coding gene Chr5:134515952-134521201 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029937
 protein coding gene Chr5:147914600-147919840 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030606
 protein coding gene Chr5:132227231-132232471 (+)
PWK/PhJ MGP_PWKPhJ_G0028953
 protein coding gene Chr5:127250739-127257196 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028789
 protein coding gene Chr5:129778361-129786510 (+)
WSB/EiJ MGP_WSBEiJ_G0029312
 protein coding gene Chr5:132928712-132933962 (+)



Homology
more
  • Human Ortholog
    NUPR2, nuclear protein 2, transcriptional regulator
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NUPR2, nuclear protein 2, transcriptional regulator
  • Synonyms
    NUPR1L, P8
  • Links
    NCBI Gene ID: 389493
    neXtProt AC: NX_A6NF83
    UniProt: A6NF83

  • Chr Location
    7p11.2; chr7:56114681-56116417 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    15
  • Chemically induced (other)
    1
  • Gene trapped
    13
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Nupr2
  • Find Mice (IMSR)
    2 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69034 NCBI Gene Model | MGI Sequence Detail 5249 C57BL/6J ±  kb
transcript NM_001359308 RefSeq | MGI Sequence Detail 832 C57BL/6  
polypeptide Q497P3 UniProt | EBI | MGI Sequence Detail 102 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916284, MGI:7525415
References
more
  • Summaries
    All 29
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory