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Arl5b Gene Detail
Summary
  • Symbol
    Arl5b
  • Name
    ADP-ribosylation factor-like 5B
  • Synonyms
    4930587A11Rik, Arl8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923119
    NCBI Gene: 75869
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:15060066-15087267 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 10.98 cM, cytoband A2
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    672 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923119
 protein coding gene Chr2:15054206-15087267 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025366
 protein coding gene Chr2:12600906-12633958 (+)
A/J MGP_AJ_G0025344
 protein coding gene Chr2:12128512-12161905 (+)
AKR/J MGP_AKRJ_G0025312
 protein coding gene Chr2:12487961-12521016 (+)
BALB/cJ MGP_BALBcJ_G0025339
 protein coding gene Chr2:12133577-12166622 (+)
C3H/HeJ MGP_C3HHeJ_G0025099
 protein coding gene Chr2:12454986-12490409 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025781
 protein coding gene Chr2:12897835-12930925 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023197
 protein coding gene Chr2:11638579-11672036 (+)
CAST/EiJ MGP_CASTEiJ_G0024562
 protein coding gene Chr2:12431032-12464150 (+)
CBA/J MGP_CBAJ_G0025078
 protein coding gene Chr2:13507175-13540325 (+)
DBA/2J MGP_DBA2J_G0025210
 protein coding gene Chr2:12033651-12067281 (+)
FVB/NJ MGP_FVBNJ_G0025172
 protein coding gene Chr2:11899330-11932391 (+)
LP/J MGP_LPJ_G0025296
 protein coding gene Chr2:12500794-12535172 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025204
 protein coding gene Chr2:13329224-13363832 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025840
 protein coding gene Chr2:12403616-12436663 (+)
PWK/PhJ MGP_PWKPhJ_G0024313
 protein coding gene Chr2:11876032-11909549 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024113
 protein coding gene Chr2:12497547-12530561 (+)
WSB/EiJ MGP_WSBEiJ_G0024632
 protein coding gene Chr2:12539324-12572361 (+)



Homology
more
  • Human Ortholog
    ARL5B, ARF like GTPase 5B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARL5B, ARF like GTPase 5B
  • Synonyms
    ARL8
  • Links
    NCBI Gene ID: 221079
    neXtProt AC: NX_Q96KC2
    UniProt: Q96KC2

  • Chr Location
    10p12.31; chr10:18659431-18681639 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    1
  • cDNA Data
    88
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 75869 NCBI Gene Model | MGI Sequence Detail 27202 C57BL/6J ±  kb
transcript NM_029466 RefSeq | MGI Sequence Detail 6901 C57BL/6  
polypeptide Q9D4P0 UniProt | EBI | MGI Sequence Detail 179 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 89
    cDNA 88
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139323
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:218760 Kitai Y, et al., Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B. J Biol Chem. 2015 Jan 9;290(2):1269-80
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory