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Adal Gene Detail
Summary
  • Symbol
    Adal
  • Name
    adenosine deaminase-like
  • Synonyms
    4930578F03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923144
    NCBI Gene: 75894
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:120970909-120987161 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 60.37 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    374 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923144
protein coding gene Chr2:120970525-120989921 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026382
protein coding gene Chr2:124024217-124040861 (+)
A/J MGP_AJ_G0026343
protein coding gene Chr2:118949440-118965781 (+)
AKR/J MGP_AKRJ_G0026322
protein coding gene Chr2:122293226-122309613 (+)
BALB/cJ MGP_BALBcJ_G0026356
protein coding gene Chr2:119186979-119203331 (+)
C3H/HeJ MGP_C3HHeJ_G0026102
protein coding gene Chr2:122771985-122790158 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026803
protein coding gene Chr2:128086858-128104223 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024183
protein coding gene Chr2:113994276-114012126 (+)
CAST/EiJ MGP_CASTEiJ_G0025564
protein coding gene Chr2:123091671-123107878 (+)
CBA/J MGP_CBAJ_G0026078
protein coding gene Chr2:132557050-132576396 (+)
DBA/2J MGP_DBA2J_G0026217
protein coding gene Chr2:118350501-118366856 (+)
FVB/NJ MGP_FVBNJ_G0026179
protein coding gene Chr2:117169589-117185986 (+)
LP/J MGP_LPJ_G0026318
protein coding gene Chr2:124281888-124299937 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026198
protein coding gene Chr2:136847020-136865768 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026858
protein coding gene Chr2:122407693-122424793 (+)
PWK/PhJ MGP_PWKPhJ_G0025300
protein coding gene Chr2:117953048-117969728 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025099
protein coding gene Chr2:121624996-121644203 (+)
WSB/EiJ MGP_WSBEiJ_G0025633
protein coding gene Chr2:123235758-123254159 (+)



Homology
more
  • Human Ortholog
    MAPDA, N6-Methyl-AMP deaminase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAPDA, N6-Methyl-AMP deaminase
  • Synonyms
    ADAL, HsMAPDA
  • Links
    NCBI Gene ID: 161823
    neXtProt AC: NX_Q6DHV7
    UniProt: Q6DHV7

  • Chr Location
    15q15.3; chr15:43330351-43354569 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027259 Ensembl Gene Model | MGI Sequence Detail 16253 C57BL/6J ±  kb
transcript ENSMUST00000119031 Ensembl | MGI Sequence Detail 2477 Not Applicable  
polypeptide ENSMUSP00000113052 Ensembl | MGI Sequence Detail 360 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 55
    cDNA 55

    Microarray probesets 5
References
more
  • Summaries
    All 38
    Gene Ontology 4
    Phenotypes 13
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory