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Ganc Gene Detail
Summary
  • Symbol
    Ganc
  • Name
    glucosidase, alpha; neutral C
  • Synonyms
    5830445O15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923301
    NCBI Gene: 76051
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:120234377-120291347 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 60.31 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1437 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923301
 protein coding gene Chr2:120234377-120292181 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026366
 protein coding gene Chr2:123270732-123329498 (+)
A/J MGP_AJ_G0026327
 protein coding gene Chr2:118217555-118276259 (+)
AKR/J MGP_AKRJ_G0026306
 protein coding gene Chr2:121519204-121579756 (+)
BALB/cJ MGP_BALBcJ_G0026340
 protein coding gene Chr2:118461503-118519105 (+)
C3H/HeJ MGP_C3HHeJ_G0026086
 protein coding gene Chr2:121993422-122064376 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026787
 protein coding gene Chr2:127282431-127345368 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024167
 protein coding gene Chr2:113238964-113296964 (+)
CAST/EiJ MGP_CASTEiJ_G0025548
 protein coding gene Chr2:122305465-122369662 (+)
CBA/J MGP_CBAJ_G0026062
 protein coding gene Chr2:131737470-131803261 (+)
DBA/2J MGP_DBA2J_G0026201
 protein coding gene Chr2:117607753-117665369 (+)
FVB/NJ MGP_FVBNJ_G0026163
 protein coding gene Chr2:116443636-116503590 (+)
LP/J MGP_LPJ_G0026302
 protein coding gene Chr2:123526500-123588169 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026182
 protein coding gene Chr2:136050415-136113809 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026842
 protein coding gene Chr2:121644689-121706970 (+)
PWK/PhJ MGP_PWKPhJ_G0025284
 protein coding gene Chr2:117210164-117272128 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025083
 protein coding gene Chr2:120841004-120904006 (+)
WSB/EiJ MGP_WSBEiJ_G0025617
 protein coding gene Chr2:122478815-122539351 (+)



Homology
more
  • Human Ortholog
    GANC, glucosidase alpha, neutral C
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GANC, glucosidase alpha, neutral C
  • Links
    NCBI Gene ID: 2595
    neXtProt AC: NX_Q8TET4
    UniProt: Q8TET4

  • Chr Location
    15q15.1; chr15:42273201-42353666 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    13
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76051 NCBI Gene Model | MGI Sequence Detail 56971 C57BL/6J ±  kb
transcript NM_172672 RefSeq | MGI Sequence Detail 4818 C57BL/6  
polypeptide Q8BVW0 UniProt | EBI | MGI Sequence Detail 898 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 15
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:240028 Bulusu V, et al., Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017 Feb 27;40(4):331-341.e4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory