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Ptbp3 Gene Detail
Summary
  • Symbol
    Ptbp3
  • Name
    polypyrimidine tract binding protein 3
  • Synonyms
    5830471K22Rik, MGC:11742, Rod1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923334
    NCBI Gene: 230257
  • Alliance
    gene page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:59471868-59549288 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 32.57 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1505 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923334
 protein coding gene Chr4:59471868-59549364 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028336
 protein coding gene Chr4:58375337-58454657 (-)
A/J MGP_AJ_G0028297
 protein coding gene Chr4:56133183-56209249 (-)
AKR/J MGP_AKRJ_G0028246
 protein coding gene Chr4:57699150-57779135 (-)
BALB/cJ MGP_BALBcJ_G0028316
 protein coding gene Chr4:56307508-56384110 (-)
C3H/HeJ MGP_C3HHeJ_G0028037
 protein coding gene Chr4:58237245-58317652 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028757
 protein coding gene Chr4:60415054-60493019 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026063
 protein coding gene Chr4:52865232-52941913 (-)
CAST/EiJ MGP_CASTEiJ_G0027475
 protein coding gene Chr4:57955775-58037529 (-)
CBA/J MGP_CBAJ_G0028002
 protein coding gene Chr4:62466305-62552025 (-)
DBA/2J MGP_DBA2J_G0028152
 protein coding gene Chr4:56033348-56109788 (-)
FVB/NJ MGP_FVBNJ_G0028119
 protein coding gene Chr4:55239560-55317007 (-)
LP/J MGP_LPJ_G0028251
 protein coding gene Chr4:58471460-58549400 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028143
 protein coding gene Chr4:65587636-65672229 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028793
 protein coding gene Chr4:57884726-57966572 (-)
PWK/PhJ MGP_PWKPhJ_G0027200
 protein coding gene Chr4:56067231-56147782 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027028
 protein coding gene Chr4:57214471-57293657 (-)
WSB/EiJ MGP_WSBEiJ_G0027553
 protein coding gene Chr4:57870962-57951151 (-)



Homology
more
  • Human Ortholog
    PTBP3, polypyrimidine tract binding protein 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PTBP3, polypyrimidine tract binding protein 3
  • Synonyms
    ROD1
  • Links
    NCBI Gene ID: 9991
    neXtProt AC: NX_O95758
    UniProt: O95758

  • Chr Location
    9q32; chr9:112217715-112379882 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    806
  • Tissues
    40
  • cDNA Data
    19
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 230257 NCBI Gene Model | MGI Sequence Detail 77421 C57BL/6J ±  kb
transcript NM_001404433 RefSeq | MGI Sequence Detail 7430 C57BL/6  
polypeptide Q8BHD7 UniProt | EBI | MGI Sequence Detail 523 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    Genomic 1
    cDNA 20
    Primer pair 3

    Microarray probesets 6
Other
Accession IDs
less
MGI:2140120, MGI:2140297, MGI:2140554, MGI:2140702
References
more
  • Summaries
    All 47
    Developmental Gene Expression 7
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory