About   Help   FAQ
Depdc1a Gene Detail
Summary
  • Symbol
    Depdc1a
  • Name
    DEP domain containing 1a
  • Synonyms
    5830484J08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923381
    NCBI Gene: 76131
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:159201070-159235592 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 82.47 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    579 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923381
 protein coding gene Chr3:159201042-159235690 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028018
 protein coding gene Chr3:163653679-163692650 (+)
A/J MGP_AJ_G0027976
 protein coding gene Chr3:157753499-157789526 (+)
AKR/J MGP_AKRJ_G0027942
 protein coding gene Chr3:161903320-161937621 (+)
BALB/cJ MGP_BALBcJ_G0027988
 protein coding gene Chr3:157548555-157585172 (+)
C3H/HeJ MGP_C3HHeJ_G0027718
 protein coding gene Chr3:162289184-162324993 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028431
 protein coding gene Chr3:169007408-169047147 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025770
 protein coding gene Chr3:152190758-152221252 (+)
CAST/EiJ MGP_CASTEiJ_G0027171
 protein coding gene Chr3:162408070-162452241 (+)
CBA/J MGP_CBAJ_G0027693
 protein coding gene Chr3:174984505-175024954 (+)
DBA/2J MGP_DBA2J_G0027833
 protein coding gene Chr3:156743710-156787320 (+)
FVB/NJ MGP_FVBNJ_G0027800
 protein coding gene Chr3:154082491-154122308 (+)
LP/J MGP_LPJ_G0027944
 protein coding gene Chr3:165005884-165040961 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027833
 protein coding gene Chr3:183808630-183859205 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028490
 protein coding gene Chr3:161534966-161568131 (+)
PWK/PhJ MGP_PWKPhJ_G0026894
 protein coding gene Chr3:156653782-156689290 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026722
 protein coding gene Chr3:159810423-159848139 (+)
WSB/EiJ MGP_WSBEiJ_G0027251
 protein coding gene Chr3:162512167-162546938 (+)



Homology
more
  • Human Ortholog
    DEPDC1, DEP domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DEPDC1, DEP domain containing 1
  • Synonyms
    DEP.8, DEPDC1A, DEPDC1-V2, SDP35
  • Links
    NCBI Gene ID: 55635
    neXtProt AC: NX_Q5TB30
    UniProt: Q5TB30

  • Chr Location
    1p31.3; chr1:68474152-68497221 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    35
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028175 Ensembl Gene Model | MGI Sequence Detail 34523 C57BL/6J ±  kb
transcript ENSMUST00000120272 Ensembl | MGI Sequence Detail 3323 Not Applicable  
polypeptide ENSMUSP00000113216 Ensembl | MGI Sequence Detail 806 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    cDNA 35

    Microarray probesets 4
References
more
  • Summaries
    All 28
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory