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Haus6 Gene Detail
Summary
  • Symbol
    Haus6
  • Name
    HAUS augmin-like complex, subunit 6
  • Synonyms
    6230416J20Rik, D4Ertd27e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923389
    NCBI Gene: 230376
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:86497092-86530292 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 40.69 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    964 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923389
 protein coding gene Chr4:86497092-86530317 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028412
 protein coding gene Chr4:86341437-86374658 (-)
A/J MGP_AJ_G0028373
 protein coding gene Chr4:83334113-83367391 (-)
AKR/J MGP_AKRJ_G0028322
 protein coding gene Chr4:85433324-85466645 (-)
BALB/cJ MGP_BALBcJ_G0028393
 protein coding gene Chr4:83517270-83550482 (-)
C3H/HeJ MGP_C3HHeJ_G0028108
 protein coding gene Chr4:86082178-86115532 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028832
 protein coding gene Chr4:89613049-89646912 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026132
 protein coding gene Chr4:79427571-79461469 (-)
CAST/EiJ MGP_CASTEiJ_G0027549
 protein coding gene Chr4:83985797-84021382 (-)
CBA/J MGP_CBAJ_G0028077
 protein coding gene Chr4:92399975-92433518 (-)
DBA/2J MGP_DBA2J_G0028226
 protein coding gene Chr4:83077993-83111720 (-)
FVB/NJ MGP_FVBNJ_G0028192
 protein coding gene Chr4:82065827-82099025 (-)
LP/J MGP_LPJ_G0028326
 protein coding gene Chr4:86676516-86709739 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028221
 protein coding gene Chr4:97453402-97487420 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028869
 protein coding gene Chr4:85507089-85540307 (-)
PWK/PhJ MGP_PWKPhJ_G0027272
 protein coding gene Chr4:81423282-81457158 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027097
 protein coding gene Chr4:83059830-83097923 (-)
WSB/EiJ MGP_WSBEiJ_G0027625
 protein coding gene Chr4:85691407-85725905 (-)



Homology
more
  • Human Ortholog
    HAUS6, HAUS augmin like complex subunit 6
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HAUS6, HAUS augmin like complex subunit 6
  • Synonyms
    Dgt6, FAM29A
  • Links
    NCBI Gene ID: 54801
    neXtProt AC: NX_Q7Z4H7
    UniProt: Q7Z4H7

  • Chr Location
    9p22.1; chr9:19053141-19102904 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit embryonic lethality between E2.5 and E7.5 with delayed or incomplete clustering of microtubule-organizing centers.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    851
  • Tissues
    145
  • cDNA Data
    67
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000038047 Ensembl Gene Model | MGI Sequence Detail 33201 C57BL/6J ±  kb
    transcript ENSMUST00000070607 Ensembl | MGI Sequence Detail 6158 Not Applicable  
    polypeptide ENSMUSP00000070504 Ensembl | MGI Sequence Detail 933 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      7 Sequences
    • InterPro Domains
      IPR026797 HAUS augmin-like complex subunit 6
      IPR028163 HAUS augmin-like complex subunit 6, N-terminal
    Molecular
    Reagents
    less
    • All nucleic 70
      cDNA 67
      Primer pair 2
      Other 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1098820
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 4
      Gene Ontology 2
      Phenotypes 12
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:334667 Schweizer N, et al., Sub-centrosomal mapping identifies augmin-gammaTuRC as part of a centriole-stabilizing scaffold. Nat Commun. 2021 Oct 15;12(1):6042
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory