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Stx16 Gene Detail
Summary
  • Symbol
    Stx16
  • Name
    syntaxin 16
  • Synonyms
    5430410K23Rik, 6330500A18Rik, SYN16
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923396
    NCBI Gene: 228960
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:173918101-173941564 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 97.85 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    421 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923396
 protein coding gene Chr2:173918052-173941564 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026962
 protein coding gene Chr2:180412258-180436037 (+)
A/J MGP_AJ_G0026929
 protein coding gene Chr2:172809520-172833550 (+)
AKR/J MGP_AKRJ_G0026900
 protein coding gene Chr2:178015267-178038505 (+)
BALB/cJ MGP_BALBcJ_G0026938
 protein coding gene Chr2:173200646-173224313 (+)
C3H/HeJ MGP_C3HHeJ_G0026680
 protein coding gene Chr2:178398355-178422838 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027385
 protein coding gene Chr2:185603898-185627205 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024754
 protein coding gene Chr2:166052444-166075862 (+)
CAST/EiJ MGP_CASTEiJ_G0026139
 protein coding gene Chr2:179126667-179150132 (+)
CBA/J MGP_CBAJ_G0026657
 protein coding gene Chr2:192518057-192547030 (+)
DBA/2J MGP_DBA2J_G0026795
 protein coding gene Chr2:171902346-171928235 (+)
FVB/NJ MGP_FVBNJ_G0026761
 protein coding gene Chr2:170527360-170551369 (+)
LP/J MGP_LPJ_G0026896
 protein coding gene Chr2:180328919-180352320 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026780
 protein coding gene Chr2:195422545-195446928 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027442
 protein coding gene Chr2:178042751-178065996 (+)
PWK/PhJ MGP_PWKPhJ_G0025875
 protein coding gene Chr2:171717294-171740837 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025675
 protein coding gene Chr2:177078534-177101756 (+)
WSB/EiJ MGP_WSBEiJ_G0026211
 protein coding gene Chr2:179007648-179031797 (+)



Homology
more
  • Human Ortholog
    STX16, syntaxin 16
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STX16, syntaxin 16
  • Synonyms
    SYN-16, SYN16
  • Links
    NCBI Gene ID: 8675
    neXtProt AC: NX_O14662
    UniProt: O14662

  • Chr Location
    20q13.32; chr20:58651272-58679526 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human STX16 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele are viable and fertile and do not exhibit methylation abnormalities or develop a pseudohypoparathyroidism resistance phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    38
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    781
  • Tissues
    45
  • cDNA Data
    81
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027522 Ensembl Gene Model | MGI Sequence Detail 23464 C57BL/6J ±  kb
    transcript ENSMUST00000087908 Ensembl | MGI Sequence Detail 3865 Not Applicable  
    polypeptide ENSMUSP00000085218 Ensembl | MGI Sequence Detail 326 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 81
      cDNA 81

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1914046, MGI:2139029, MGI:2139392
    References
    more
    • Summaries
      All 49
      Developmental Gene Expression 4
      Gene Ontology 12
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory