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Igsf10 Gene Detail
Summary
  • Symbol
    Igsf10
  • Name
    immunoglobulin superfamily, member 10
  • Synonyms
    6530405F15Rik, Adlican2, CMF608
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923481
    NCBI Gene: 242050
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:59224156-59251815 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 29.03 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    685 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923481
protein coding gene Chr3:59224156-59256836 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027247
protein coding gene Chr3:58188537-58220066 (-)
A/J MGP_AJ_G0027207
protein coding gene Chr3:56368873-56396195 (-)
AKR/J MGP_AKRJ_G0027177
protein coding gene Chr3:57544314-57571945 (-)
BALB/cJ MGP_BALBcJ_G0027220
protein coding gene Chr3:56176589-56203809 (-)
C3H/HeJ MGP_C3HHeJ_G0026963
protein coding gene Chr3:57760118-57787470 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027666
protein coding gene Chr3:60336872-60370303 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025020
protein coding gene Chr3:52728618-52756652 (-)
CAST/EiJ MGP_CASTEiJ_G0026415
protein coding gene Chr3:57940060-57968858 (-)
CBA/J MGP_CBAJ_G0026939
protein coding gene Chr3:62331856-62361855 (-)
DBA/2J MGP_DBA2J_G0027073
protein coding gene Chr3:55882850-55911209 (-)
FVB/NJ MGP_FVBNJ_G0027041
protein coding gene Chr3:54829447-54858105 (-)
LP/J MGP_LPJ_G0027185
protein coding gene Chr3:58944594-58972974 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027059
protein coding gene Chr3:66474952-66513828 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027724
protein coding gene Chr3:57518139-57546870 (-)
PWK/PhJ MGP_PWKPhJ_G0026147
protein coding gene Chr3:55518560-55546818 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025960
protein coding gene Chr3:57220764-57246967 (-)
WSB/EiJ MGP_WSBEiJ_G0026489
protein coding gene Chr3:57594351-57623317 (-)



Homology
more
  • Human Ortholog
    IGSF10, immunoglobulin superfamily member 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGSF10, immunoglobulin superfamily member 10
  • Synonyms
    CMF608
  • Links
    NCBI Gene ID: 285313
    neXtProt AC: NX_Q6WRI0
    UniProt: Q6WRI0

  • Chr Location
    3q25.1; chr3:151425384-151619925 (-)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036334 Ensembl Gene Model | MGI Sequence Detail 27660 C57BL/6J ±  kb
transcript ENSMUST00000193455 Ensembl | MGI Sequence Detail 8484 Not Applicable  
polypeptide ENSMUSP00000141971 Ensembl | MGI Sequence Detail 2594 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000008969 immunoglobulin superfamily member 10
  • InterPro Domains
    IPR000483 Cysteine-rich flanking region, C-terminal
    IPR013098 Immunoglobulin I-set
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003599 Immunoglobulin subtype
    IPR003598 Immunoglobulin subtype 2
    IPR013106 Immunoglobulin V-set domain
    IPR001611 Leucine-rich repeat
    IPR050467 Leucine-rich repeat and fibronectin type-III domain-containing
    IPR032675 Leucine-rich repeat domain superfamily
    IPR000372 Leucine-rich repeat N-terminal domain
    IPR003591 Leucine-rich repeat, typical subtype
  • GlyGen
    Q3V1M1 17 sites, 5 N-linked glycans (10 sites), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 16
    cDNA 13
    Primer pair 2
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2139569, MGI:2139590, MGI:2139693
References
more
  • Summaries
    All 32
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory