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Pcgf5 Gene Detail
Summary
  • Symbol
    Pcgf5
  • Name
    polycomb group ring finger 5
  • Synonyms
    0610009F02Rik, 1110054A01Rik, 5830406C17Rik, 5830443C21Rik, 9530023M17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923505
    NCBI Gene: 76073
  • Alliance
    gene page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:36325729-36438370 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 31.59 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3132 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923505
 protein coding gene Chr19:36325709-36438370 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025071
 protein coding gene Chr19:35243576-35338375 (+)
A/J MGP_AJ_G0025047
 protein coding gene Chr19:33568189-33653102 (+)
AKR/J MGP_AKRJ_G0025015
 protein coding gene Chr19:34681546-34771459 (+)
BALB/cJ MGP_BALBcJ_G0025045
 protein coding gene Chr19:33651360-33735927 (+)
C3H/HeJ MGP_C3HHeJ_G0024804
 protein coding gene Chr19:34757910-34838884 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025486
 protein coding gene Chr19:36263715-36352574 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022904
 protein coding gene Chr19:32938424-33016324 (+)
CAST/EiJ MGP_CASTEiJ_G0024271
 protein coding gene Chr19:34550258-34646464 (+)
CBA/J MGP_CBAJ_G0024781
 protein coding gene Chr19:37980240-38071762 (+)
DBA/2J MGP_DBA2J_G0024913
 protein coding gene Chr19:33426022-33510894 (+)
FVB/NJ MGP_FVBNJ_G0024874
 protein coding gene Chr19:33235587-33312695 (+)
LP/J MGP_LPJ_G0024999
 protein coding gene Chr19:35338758-35420736 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024905
 protein coding gene Chr19:37801220-37888705 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025544
 protein coding gene Chr19:34777402-34864637 (+)
PWK/PhJ MGP_PWKPhJ_G0024023
 protein coding gene Chr19:33242860-33324205 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023823
 protein coding gene Chr19:33649159-33703302 (+)
WSB/EiJ MGP_WSBEiJ_G0024338
 protein coding gene Chr19:34848136-34966441 (+)



Homology
more
  • Human Ortholog
    PCGF5, polycomb group ring finger 5
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCGF5, polycomb group ring finger 5
  • Synonyms
    RNF159
  • Links
    NCBI Gene ID: 84333
    neXtProt AC: NX_Q86SE9
    UniProt: Q86SE9

  • Chr Location
    10q23.32; chr10:91156219-91284337 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Bone marrow cells from mice homozygous for a conditional allele exhibit normal hematopoietic and progenitor cell function.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    780
  • Tissues
    50
  • cDNA Data
    17
  • Literature Summary
    7
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 76073 NCBI Gene Model | MGI Sequence Detail 112642 C57BL/6J ±  kb
transcript NM_001368690 RefSeq | MGI Sequence Detail 6483 C57BL/6  
polypeptide Q3UK78 UniProt | EBI | MGI Sequence Detail 256 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    Genomic 2
    cDNA 17
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:1916085, MGI:1923323, MGI:1924847, MGI:1925910, MGI:2147508
References
more
  • Summaries
    All 43
    Developmental Gene Expression 7
    Gene Ontology 8
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:338403 Cho KW, et al., Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation Through Modulation of the TARDBP/RBM38 Axis. Circulation. 2023 Jun 13;147(24):1823-1842
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory