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Pfdn4 Gene Detail
Summary
  • Symbol
    Pfdn4
  • Name
    prefoldin 4
  • Synonyms
    0610025M10Rik, 1810063B06Rik, C-1, C1, PFD4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923512
    NCBI Gene: 109054
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:170338348-170360987 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 91.91 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    981 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923512
 protein coding gene Chr2:170338348-170361043 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026936
 protein coding gene Chr2:176561700-176569330 (+)
A/J MGP_AJ_G0026903
 protein coding gene Chr2:169175579-169200347 (+)
AKR/J MGP_AKRJ_G0026874
 protein coding gene Chr2:174255775-174263405 (+)
BALB/cJ MGP_BALBcJ_G0026912
 protein coding gene Chr2:169566646-169574276 (+)
C3H/HeJ MGP_C3HHeJ_G0026654
 protein coding gene Chr2:174625707-174633337 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027359
 protein coding gene Chr2:181660397-181668027 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024729
 protein coding gene Chr2:162483463-162495583 (+)
CAST/EiJ MGP_CASTEiJ_G0026112
 protein coding gene Chr2:175236522-175245012 (+)
CBA/J MGP_CBAJ_G0026631
 protein coding gene Chr2:188433284-188440914 (+)
DBA/2J MGP_DBA2J_G0026769
 protein coding gene Chr2:168282823-168290453 (+)
FVB/NJ MGP_FVBNJ_G0026735
 protein coding gene Chr2:166886102-166893749 (+)
LP/J MGP_LPJ_G0026870
 protein coding gene Chr2:176518751-176526381 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026754
 protein coding gene Chr2:191513149-191537350 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027416
 protein coding gene Chr2:174215335-174222982 (+)
PWK/PhJ MGP_PWKPhJ_G0025849
 protein coding gene Chr2:167992593-168016606 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025649
 protein coding gene Chr2:173220664-173229312 (+)
WSB/EiJ MGP_WSBEiJ_G0026185
 protein coding gene Chr2:175178221-175185859 (+)



Homology
more
  • Human Ortholog
    PFDN4, prefoldin subunit 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PFDN4, prefoldin subunit 4
  • Synonyms
    C1, PFD4
  • Links
    NCBI Gene ID: 5203
    neXtProt AC: NX_Q9NQP4
    UniProt: Q9NQP4

  • Chr Location
    20q13.2; chr20:54208087-54228052 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    76
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 109054 NCBI Gene Model | MGI Sequence Detail 22640 C57BL/6J ±  kb
transcript NM_001013369 RefSeq | MGI Sequence Detail 816 ZRU/MplStud  
polypeptide NP_001103622 RefSeq | MGI Sequence Detail 134 ZRU/MplStud  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR002777 Prefoldin beta-like
    IPR016661 Prefoldin, subunit 4
  • GlyGen
    Q3UWL8 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 76
    cDNA 76

    Microarray probesets 2
Other
Accession IDs
less
MGI:1923967
References
more
  • Summaries
    All 24
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory