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Pbp2 Gene Detail
Summary
  • Symbol
    Pbp2
  • Name
    phosphatidylethanolamine binding protein 2
  • Synonyms
    1700023A18Rik, Pebp-2, Pebp2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923650
    NCBI Gene: 76400
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:135286127-135287382 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 66.17 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    168 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923650
 protein coding gene Chr6:135286125-135287403 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031418
 protein coding gene Chr6:139654190-139655468 (-)
A/J MGP_AJ_G0031394
 protein coding gene Chr6:134132537-134133815 (-)
AKR/J MGP_AKRJ_G0031321
 protein coding gene Chr6:138216888-138218166 (-)
BALB/cJ MGP_BALBcJ_G0031400
 protein coding gene Chr6:133974447-133975726 (-)
C3H/HeJ MGP_C3HHeJ_G0031122
 protein coding gene Chr6:138256339-138257617 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031860
 protein coding gene Chr6:143453990-143455268 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028992
 protein coding gene Chr6:133292858-133294132 (-)
CAST/EiJ MGP_CASTEiJ_G0030491
 protein coding gene Chr6:137701098-137702373 (-)
CBA/J MGP_CBAJ_G0031081
 protein coding gene Chr6:148786311-148787589 (-)
DBA/2J MGP_DBA2J_G0031239
 protein coding gene Chr6:132987547-132988825 (-)
FVB/NJ MGP_FVBNJ_G0031189
 protein coding gene Chr6:131908108-131909386 (-)
LP/J MGP_LPJ_G0031323
 protein coding gene Chr6:139738376-139739654 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031229
 protein coding gene Chr6:152803092-152804370 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031893
 protein coding gene Chr6:137984462-137985741 (-)
PWK/PhJ MGP_PWKPhJ_G0030216
 protein coding gene Chr6:131492365-131493643 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030040
 protein coding gene Chr6:136152191-136153472 (-)
WSB/EiJ MGP_WSBEiJ_G0030582
 protein coding gene Chr6:138607146-138608424 (-)



Homology
more
  • Human Ortholog
    PEBP1, phosphatidylethanolamine binding protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PEBP1, phosphatidylethanolamine binding protein 1
  • Synonyms
    HCNP, HCNPpp, HEL-210, HEL-S-34, HEL-S-96, PBP, PEBP, PEBP-1, RKIP
  • Links
    NCBI Gene ID: 5037
    neXtProt AC: NX_P30086
    UniProt: P30086

  • Chr Location
    12q24.23; chr12:118136124-118145584 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human PEBP1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76400 NCBI Gene Model | MGI Sequence Detail 1256 C57BL/6J ±  kb
transcript NM_029595 RefSeq | MGI Sequence Detail 1256 Not Specified  
polypeptide Q8VIN1 UniProt | EBI | MGI Sequence Detail 187 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
Other
Accession IDs
less
MGI:1889813
References
more
  • Summaries
    All 25
    Gene Ontology 4
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:91808 Kazuki Y, et al., Human chromosome 21q22.2-qter carries a gene(s) responsible for downregulation of mlc2a and PEBP in Down syndrome model mice. Biochem Biophys Res Commun. 2004 Apr 30;317(2):491-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory