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Saxo5 Gene Detail
Summary
  • Symbol
    Saxo5
  • Name
    stabilizer of axonemal microtubules 5
  • Synonyms
    1700019B03Rik, Tex45
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923656
    NCBI Gene: 76406
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:3520862-3537181 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 1.92 cM, cytoband A1.1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    387 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923656
 protein coding gene Chr8:3515966-3537183 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033303
 protein coding gene Chr8:379759-401652 (+)
A/J MGP_AJ_G0033286
 protein coding gene Chr8:379894-396912 (+)
AKR/J MGP_AKRJ_G0033217
 protein coding gene Chr8:393824-409628 (+)
BALB/cJ MGP_BALBcJ_G0033286
 protein coding gene Chr8:407591-424060 (+)
C3H/HeJ MGP_C3HHeJ_G0033000
 protein coding gene Chr8:404331-422331 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033796
 protein coding gene Chr8:417324-436931 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030769
 protein coding gene Chr8:337117-353495 (+)
CAST/EiJ MGP_CASTEiJ_G0032323
 protein coding gene Chr8:404789-424011 (+)
CBA/J MGP_CBAJ_G0032973
 protein coding gene Chr8:426223-447756 (+)
DBA/2J MGP_DBA2J_G0033127
 protein coding gene Chr8:347219-362952 (+)
FVB/NJ MGP_FVBNJ_G0033074
 protein coding gene Chr8:401213-419244 (+)
LP/J MGP_LPJ_G0033219
 protein coding gene Chr8:385373-408568 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033109
 protein coding gene Chr8:423277-443559 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033814
 protein coding gene Chr8:378525-402597 (+)
PWK/PhJ MGP_PWKPhJ_G0032033
 protein coding gene Chr8:368412-384816 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031877
 protein coding gene Chr8:378545-397607 (+)
WSB/EiJ MGP_WSBEiJ_G0032436
 protein coding gene Chr8:383775-401985 (+)



Homology
more
  • Human Ortholog
    SAXO5, stabilizer of axonemal microtubules 5
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SAXO5, stabilizer of axonemal microtubules 5
  • Synonyms
    C19orf45, TEX45
  • Links
    NCBI Gene ID: 374877
    neXtProt AC: NX_Q8NA69
    UniProt: Q8NA69

  • Chr Location
    19p13.2; chr19:7492976-7508450 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    4
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040340 Ensembl Gene Model | MGI Sequence Detail 16320 C57BL/6J ±  kb
transcript ENSMUST00000047265 Ensembl | MGI Sequence Detail 1613 Not Applicable  
polypeptide ENSMUSP00000043586 Ensembl | MGI Sequence Detail 500 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR028001 Stabilizer of axonemal microtubules 5
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
Other
Accession IDs
less
MGI:5882226, MGI:7482224
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory