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Cep112 Gene Detail
Summary
  • Symbol
    Cep112
  • Name
    centrosomal protein 112
  • Synonyms
    1700001M19Rik, 1700029K01Rik, 8430407H02Rik, Ccdc46, Macoco
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923673
    NCBI Gene: 76380
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:108316041-108751441 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 71.83 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    10714 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923673
 protein coding gene Chr11:108316018-108751441 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019327
 protein coding gene Chr11:111892675-112347363 (+)
A/J MGP_AJ_G0019295
 protein coding gene Chr11:107072206-107516972 (+)
AKR/J MGP_AKRJ_G0019264
 protein coding gene Chr11:110281812-110715637 (+)
BALB/cJ MGP_BALBcJ_G0019269
 protein coding gene Chr11:107502416-107951264 (+)
C3H/HeJ MGP_C3HHeJ_G0019078
 protein coding gene Chr11:110595648-111046666 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019719
 protein coding gene Chr11:115301118-115762051 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017343
 protein coding gene Chr11:104336382-104753775 (+)
CAST/EiJ MGP_CASTEiJ_G0018631
 protein coding gene Chr11:111705028-112139169 (+)
CBA/J MGP_CBAJ_G0019047
 protein coding gene Chr11:120079198-120565578 (+)
DBA/2J MGP_DBA2J_G0019159
 protein coding gene Chr11:106560049-106998573 (+)
FVB/NJ MGP_FVBNJ_G0019150
 protein coding gene Chr11:106057069-106483247 (+)
LP/J MGP_LPJ_G0019229
 protein coding gene Chr11:112327057-112771103 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019180
 protein coding gene Chr11:119261811-119741265 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019756
 protein coding gene Chr11:110846866-111292054 (+)
PWK/PhJ MGP_PWKPhJ_G0018396
 protein coding gene Chr11:107709950-108145449 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018187
 protein coding gene Chr11:110596469-111055275 (+)
WSB/EiJ MGP_WSBEiJ_G0018682
 protein coding gene Chr11:110779566-111216065 (+)



Homology
more
  • Human Ortholog
    CEP112, centrosomal protein 112
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CEP112, centrosomal protein 112
  • Synonyms
    CCDC46, MACOCO, SPGF44
  • Links
    NCBI Gene ID: 201134
    neXtProt AC: NX_Q8N8E3
    UniProt: Q8N8E3

  • Chr Location
    17q24.1; chr17:65635537-66192133 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CEP112 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    27
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76380 NCBI Gene Model | MGI Sequence Detail 435401 C57BL/6J ±  kb
transcript NM_029606 RefSeq | MGI Sequence Detail 3516 C57BL/6  
polypeptide Q5PR68 UniProt | EBI | MGI Sequence Detail 954 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    cDNA 27

    Microarray probesets 5
Other
Accession IDs
less
MGI:1918712, MGI:1923630, MGI:2142738, MGI:2144454
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:357758 Zhang X, et al., CEP112 coordinates translational regulation of essential fertility genes during spermiogenesis through phase separation in humans and mice. Nat Commun. 2024 Sep 30;15(1):8465
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory