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Paqr4 Gene Detail
Summary
  • Symbol
    Paqr4
  • Name
    progestin and adipoQ receptor family member IV
  • Synonyms
    1500004C10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923748
    NCBI Gene: 76498
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:23955160-23959841 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 17, 12.02 cM, cytoband A3.3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    111 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923748
protein coding gene Chr17:23955160-23959873 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023268
protein coding gene Chr17:22653122-22657266 (-)
A/J MGP_AJ_G0023228
protein coding gene Chr17:21997740-22001894 (-)
AKR/J MGP_AKRJ_G0023198
protein coding gene Chr17:22078435-22082599 (-)
BALB/cJ MGP_BALBcJ_G0023233
protein coding gene Chr17:22215184-22219343 (-)
C3H/HeJ MGP_C3HHeJ_G0022993
protein coding gene Chr17:22437275-22441439 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023676
protein coding gene Chr17:23641431-23645575 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021157
protein coding gene Chr17:19564323-19568474 (-)
CAST/EiJ MGP_CASTEiJ_G0022499
protein coding gene Chr17:22269115-22273259 (-)
CBA/J MGP_CBAJ_G0022969
protein coding gene Chr17:24443945-24453011 (-)
DBA/2J MGP_DBA2J_G0023101
protein coding gene Chr17:21628461-21632610 (-)
FVB/NJ MGP_FVBNJ_G0023068
protein coding gene Chr17:21352702-21357194 (-)
LP/J MGP_LPJ_G0023175
protein coding gene Chr17:22904330-22908489 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023087
protein coding gene Chr17:24205938-24211306 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023715
protein coding gene Chr17:22374941-22379096 (-)
PWK/PhJ MGP_PWKPhJ_G0022247
protein coding gene Chr17:20414999-20419143 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022067
protein coding gene Chr17:20392392-20396525 (-)
WSB/EiJ MGP_WSBEiJ_G0022562
protein coding gene Chr17:22424910-22429057 (-)



Homology
more
  • Human Ortholog
    PAQR4, progestin and adipoQ receptor family member 4
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PAQR4, progestin and adipoQ receptor family member 4
  • Links
    NCBI Gene ID: 124222
    neXtProt AC: NX_Q8N4S7
    UniProt: Q8N4S7

  • Chr Location
    16p13.3; chr16:2969270-2973484 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023909 Ensembl Gene Model | MGI Sequence Detail 4682 C57BL/6J ±  kb
transcript ENSMUST00000024702 Ensembl | MGI Sequence Detail 2575 Not Applicable  
polypeptide ENSMUSP00000024702 Ensembl | MGI Sequence Detail 273 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 4
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:352590 Zhu Q, et al., PAQR4 regulates adipocyte function and systemic metabolic health by mediating ceramide levels. Nat Metab. 2024 Jul;6(7):1347-1366

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory