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Pcmtd2 Gene Detail
Summary
  • Symbol
    Pcmtd2
  • Name
    protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
  • Synonyms
    5330414D10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923927
    NCBI Gene: 245867
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:181479647-181499254 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 103.81 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    337 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923927
 protein coding gene Chr2:181471952-181499254 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027038
 protein coding gene Chr2:188465470-188485638 (+)
A/J MGP_AJ_G0027004
 protein coding gene Chr2:180689364-180708865 (+)
AKR/J MGP_AKRJ_G0026974
 protein coding gene Chr2:186116765-186136485 (+)
BALB/cJ MGP_BALBcJ_G0027012
 protein coding gene Chr2:181172148-181191725 (+)
C3H/HeJ MGP_C3HHeJ_G0026754
 protein coding gene Chr2:186455848-186475813 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027458
 protein coding gene Chr2:193910416-193929722 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024822
 protein coding gene Chr2:171372041-171393962 (+)
CAST/EiJ MGP_CASTEiJ_G0026213
 protein coding gene Chr2:184740133-184759511 (+)
CBA/J MGP_CBAJ_G0026731
 protein coding gene Chr2:200948700-200970179 (+)
DBA/2J MGP_DBA2J_G0026868
 protein coding gene Chr2:179792780-179812036 (+)
FVB/NJ MGP_FVBNJ_G0026834
 protein coding gene Chr2:178420083-178440446 (+)
LP/J MGP_LPJ_G0026970
 protein coding gene Chr2:188487063-188508920 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026854
 protein coding gene Chr2:203481189-203503704 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027518
 protein coding gene Chr2:186093096-186114012 (+)
PWK/PhJ MGP_PWKPhJ_G0025949
 protein coding gene Chr2:177323532-177343900 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025749
 protein coding gene Chr2:182582073-182601349 (+)
WSB/EiJ MGP_WSBEiJ_G0026285
 protein coding gene Chr2:187068608-187087919 (+)



Homology
more
  • Human Ortholog
    PCMTD2, protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCMTD2, protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
  • Synonyms
    C20orf36
  • Links
    NCBI Gene ID: 55251
    neXtProt AC: NX_Q9NV79
    UniProt: Q9NV79

  • Chr Location
    20q13.33; chr20:64255695-64304820 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    3
  • cDNA Data
    121
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027589 Ensembl Gene Model | MGI Sequence Detail 19608 C57BL/6J ±  kb
transcript ENSMUST00000029116 Ensembl | MGI Sequence Detail 3569 Not Applicable  
polypeptide ENSMUSP00000029116 Ensembl | MGI Sequence Detail 359 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000030718 protein-L-isoaspartate O-methyltransferase domain-containing protein 2
    (term hierarchy)
  • InterPro Domains
    IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
Molecular
Reagents
less
  • All nucleic 122
    cDNA 122

    Microarray probesets 2
Other
Accession IDs
less
MGI:2138877
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory