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Zfp998 Gene Detail
Summary
  • Symbol
    Zfp998
  • Name
    zinc finger protein 998
  • Synonyms
    2410141K09Rik, 4930482J15Rik, Gt(Ayu21)35Imeg, Gt(pU21)35Imeg, Snerv1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924053
    NCBI Gene: 76803
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:66566173-66589179 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 34.52 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    244 from dbSNP Build 142
  • Strain Annotations
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924053
 protein coding gene Chr13:66566173-66589190 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ZNF117, zinc finger protein 117
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF117, zinc finger protein 117
  • Synonyms
    HPF9, H-plk
  • Links
    NCBI Gene ID: 51351
    neXtProt AC: NX_Q03924
    UniProt: Q03924

  • Chr Location
    7q11.21
  • Human Ortholog
    ZNF490, zinc finger protein 490
  • Links
    NCBI Gene ID: 57474
    neXtProt AC: NX_Q9ULM2
    UniProt: Q9ULM2

  • Chr Location
    19p13.2-p13.13; chr19:12576100-12640098 (-)  GRCh38
  • Human Ortholog
    ZNF708, zinc finger protein 708
  • Synonyms
    KOX8, ZNF15, ZNF15L1
  • Links
    NCBI Gene ID: 7562
    neXtProt AC: NX_P17019
    UniProt: P17019

  • Chr Location
    chr19:21291160-21329425 (-)  GRCh38
  • Human Ortholog
    ZNF716, zinc finger protein 716
  • Links
    NCBI Gene ID: 441234
    neXtProt AC: NX_A6NP11
    UniProt: A6NP11

  • Chr Location
    7p11.2; chr7:57450177-57473559 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from multigenic genotypes
    7 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Genomic Mutations
    1 involving Zfp998
  • Find Mice (IMSR)
    29 strains or lines available
Homozygous knockout causes de-repression of non-ecotropic endogenous retrovirus (NEERV) transcription.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074832 Ensembl Gene Model | MGI Sequence Detail 23007 C57BL/6J ±  kb
transcript ENSMUST00000172579 Ensembl | MGI Sequence Detail 2587 Not Applicable  
polypeptide ENSMUSP00000134352 Ensembl | MGI Sequence Detail 464 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
Other
Accession IDs
less
MGI:1925258, MGI:3629747, MGI:6455696
References
more
  • Summaries
    All 24
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:343949 Young GR, et al., Gv1, a Zinc Finger Gene Controlling Endogenous MLV Expression. Mol Biol Evol. 2021 May 19;38(6):2468-2474
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory