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Phf12 Gene Detail
Summary
  • Symbol
    Phf12
  • Name
    PHD finger protein 12
  • Synonyms
    2410142K10Rik, mKIAA1523, PF1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924057
    NCBI Gene: 268448
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:77873580-77921365 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 46.74 cM, cytoband B5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    773 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924057
 protein coding gene Chr11:77873515-77921365 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018759
 protein coding gene Chr11:78941391-78992527 (+)
A/J MGP_AJ_G0018725
 protein coding gene Chr11:75935675-75986202 (+)
AKR/J MGP_AKRJ_G0018695
 protein coding gene Chr11:78244479-78292556 (+)
BALB/cJ MGP_BALBcJ_G0018699
 protein coding gene Chr11:76331778-76380193 (+)
C3H/HeJ MGP_C3HHeJ_G0018512
 protein coding gene Chr11:78275610-78326656 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019150
 protein coding gene Chr11:81412166-81464884 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016785
 protein coding gene Chr11:72913608-72961335 (+)
CAST/EiJ MGP_CASTEiJ_G0018066
 protein coding gene Chr11:78708509-78758881 (+)
CBA/J MGP_CBAJ_G0018482
 protein coding gene Chr11:84965166-85017779 (+)
DBA/2J MGP_DBA2J_G0018591
 protein coding gene Chr11:75520938-75568622 (+)
FVB/NJ MGP_FVBNJ_G0018581
 protein coding gene Chr11:75103592-75150888 (+)
LP/J MGP_LPJ_G0018662
 protein coding gene Chr11:79485647-79536735 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018607
 protein coding gene Chr11:85405718-85459204 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019190
 protein coding gene Chr11:78476860-78529439 (+)
PWK/PhJ MGP_PWKPhJ_G0017837
 protein coding gene Chr11:76295098-76343915 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017628
 protein coding gene Chr11:78079572-78133252 (+)
WSB/EiJ MGP_WSBEiJ_G0018119
 protein coding gene Chr11:78290667-78341681 (+)



Homology
more
  • Human Ortholog
    PHF12, PHD finger protein 12
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PHF12, PHD finger protein 12
  • Synonyms
    PF1
  • Links
    NCBI Gene ID: 57649
    neXtProt AC: NX_Q96QT6
    UniProt: Q96QT6

  • Chr Location
    17q11.2; chr17:28905250-28951771 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    824
  • Tissues
    81
  • cDNA Data
    15
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037791 Ensembl Gene Model | MGI Sequence Detail 47786 C57BL/6J ±  kb
transcript ENSMUST00000049167 Ensembl | MGI Sequence Detail 4410 Not Applicable  
polypeptide ENSMUSP00000044990 Ensembl | MGI Sequence Detail 1003 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    Genomic 1
    cDNA 16
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 46
    Developmental Gene Expression 7
    Gene Ontology 7
    Phenotypes 15
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:244897 Graveline R, et al., The Chromatin-Associated Phf12 Protein Maintains Nucleolar Integrity and Prevents Premature Cellular Senescence. Mol Cell Biol. 2017 Mar 01;37(5)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory