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Hyal4 Gene Detail
Summary
  • Symbol
    Hyal4
  • Name
    hyaluronoglucosaminidase 4
  • Synonyms
    4632428M18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924292
    NCBI Gene: 77042
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:24748366-24766518 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 11.28 cM, cytoband A3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    705 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924292
 protein coding gene Chr6:24748328-24767661 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030499
 protein coding gene Chr6:22317572-22336077 (+)
A/J MGP_AJ_G0030472
 protein coding gene Chr6:21384677-21405127 (+)
AKR/J MGP_AKRJ_G0030399
 protein coding gene Chr6:22075047-22098497 (+)
BALB/cJ MGP_BALBcJ_G0030482
 protein coding gene Chr6:21493882-21513214 (+)
C3H/HeJ MGP_C3HHeJ_G0030195
 protein coding gene Chr6:22070488-22090379 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030936
 protein coding gene Chr6:23010633-23035046 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028147
 protein coding gene Chr6:19837821-19856364 (+)
CAST/EiJ MGP_CASTEiJ_G0029597
 protein coding gene Chr6:21932783-21954050 (+)
CBA/J MGP_CBAJ_G0030173
 protein coding gene Chr6:23795931-23822423 (+)
DBA/2J MGP_DBA2J_G0030317
 protein coding gene Chr6:21344067-21363408 (+)
FVB/NJ MGP_FVBNJ_G0030271
 protein coding gene Chr6:21105867-21125501 (+)
LP/J MGP_LPJ_G0030404
 protein coding gene Chr6:22472512-22491652 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030307
 protein coding gene Chr6:25740356-25761199 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030966
 protein coding gene Chr6:21994124-22013314 (+)
PWK/PhJ MGP_PWKPhJ_G0029311
 protein coding gene Chr6:20908344-20931301 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029147
 protein coding gene Chr6:21725082-21745608 (+)
WSB/EiJ MGP_WSBEiJ_G0029673
 protein coding gene Chr6:21965104-21985846 (+)



Homology
more
  • Human Ortholog
    HYAL4, hyaluronidase 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HYAL4, hyaluronidase 4
  • Synonyms
    CSHY, HYAL-4
  • Links
    NCBI Gene ID: 23553
    neXtProt AC: NX_Q2M3T9
    UniProt: Q2M3T9

  • Chr Location
    7q31.32; chr7:123763708-123877481 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    822
  • Tissues
    115
  • cDNA Data
    7
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 77042 NCBI Gene Model | MGI Sequence Detail 18153 C57BL/6J ±  kb
    transcript NM_029848 RefSeq | MGI Sequence Detail 2088 Not Specified  
    polypeptide Q05A56 UniProt | EBI | MGI Sequence Detail 481 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 7
      Primer pair 5

      Microarray probesets 3
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 3
      Gene Ontology 5
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory