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Ints7 Gene Detail
Summary
  • Symbol
    Ints7
  • Name
    integrator complex subunit 7
  • Synonyms
    5930412E23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924315
    NCBI Gene: 77065
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:191307748-191355800 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 96.51 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1231 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924315
 protein coding gene Chr1:191307652-191355802 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016946
 protein coding gene Chr1:198628691-198680018 (+)
A/J MGP_AJ_G0016925
 protein coding gene Chr1:190485266-190532104 (+)
AKR/J MGP_AKRJ_G0016890
 protein coding gene Chr1:196146100-196196518 (+)
BALB/cJ MGP_BALBcJ_G0016883
 protein coding gene Chr1:191165974-191213187 (+)
C3H/HeJ MGP_C3HHeJ_G0016707
 protein coding gene Chr1:196985640-197034434 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017346
 protein coding gene Chr1:204961644-205018295 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015053
 protein coding gene Chr1:181381419-181432074 (+)
CAST/EiJ MGP_CASTEiJ_G0016290
 protein coding gene Chr1:196573010-196628690 (+)
CBA/J MGP_CBAJ_G0016681
 protein coding gene Chr1:212553450-212611370 (+)
DBA/2J MGP_DBA2J_G0016787
 protein coding gene Chr1:189203730-189252453 (+)
FVB/NJ MGP_FVBNJ_G0016783
 protein coding gene Chr1:187331464-187380446 (+)
LP/J MGP_LPJ_G0016862
 protein coding gene Chr1:199825366-199872017 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016815
 protein coding gene Chr1:219234022-219283477 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017383
 protein coding gene Chr1:196007108-196055641 (+)
PWK/PhJ MGP_PWKPhJ_G0016077
 protein coding gene Chr1:188497981-188546649 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015853
 protein coding gene Chr1:195011023-195063190 (+)
WSB/EiJ MGP_WSBEiJ_G0016352
 protein coding gene Chr1:196236814-196285618 (+)



Homology
more
  • Human Ortholog
    INTS7, integrator complex subunit 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    INTS7, integrator complex subunit 7
  • Synonyms
    C1orf73, INT7
  • Links
    NCBI Gene ID: 25896
    neXtProt AC: NX_Q9NVH2
    UniProt: Q9NVH2

  • Chr Location
    1q32.3; chr1:211940399-212035557 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    718
  • Tissues
    9
  • cDNA Data
    13
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037461 Ensembl Gene Model | MGI Sequence Detail 48053 C57BL/6J ±  kb
transcript ENSMUST00000045450 Ensembl | MGI Sequence Detail 5347 Not Applicable  
polypeptide ENSMUSP00000036277 Ensembl | MGI Sequence Detail 966 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory