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Chst15 Gene Detail
Summary
  • Symbol
    Chst15
  • Name
    carbohydrate sulfotransferase 15
  • Synonyms
    4631426J05Rik, GalNAcS-6ST, MAd5, mKIAA0598
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924840
    NCBI Gene: 77590
  • Alliance
    gene page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:131837509-131918957 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 76.29 cM, cytoband F4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2419 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924840
 protein coding gene Chr7:131837508-131919227 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033111
 protein coding gene Chr7:136921545-137006978 (-)
A/J MGP_AJ_G0033093
 protein coding gene Chr7:133152905-133234734 (-)
AKR/J MGP_AKRJ_G0033025
 protein coding gene Chr7:136697021-136784825 (-)
BALB/cJ MGP_BALBcJ_G0033094
 protein coding gene Chr7:132832968-132916652 (-)
C3H/HeJ MGP_C3HHeJ_G0032808
 protein coding gene Chr7:136534494-136620161 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033605
 protein coding gene Chr7:142118742-142199480 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030576
 protein coding gene Chr7:134425056-134508844 (-)
CAST/EiJ MGP_CASTEiJ_G0032138
 protein coding gene Chr7:128410875-128498589 (-)
CBA/J MGP_CBAJ_G0032781
 protein coding gene Chr7:146957503-147046193 (-)
DBA/2J MGP_DBA2J_G0032933
 protein coding gene Chr7:131165384-131246800 (-)
FVB/NJ MGP_FVBNJ_G0032886
 protein coding gene Chr7:130991078-131072842 (-)
LP/J MGP_LPJ_G0033027
 protein coding gene Chr7:138413523-138501102 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032918
 protein coding gene Chr7:147916021-148000044 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033625
 protein coding gene Chr7:135684200-135769343 (-)
PWK/PhJ MGP_PWKPhJ_G0031844
 protein coding gene Chr7:124177225-124260834 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031690
 protein coding gene Chr7:122473723-122558345 (-)
WSB/EiJ MGP_WSBEiJ_G0032249
 protein coding gene Chr7:136590932-136673751 (-)



Homology
more
  • Human Ortholog
    CHST15, carbohydrate sulfotransferase 15
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CHST15, carbohydrate sulfotransferase 15
  • Synonyms
    BRAG, GALNAC4S-6ST
  • Links
    NCBI Gene ID: 51363
    neXtProt AC: NX_Q7LFX5
    UniProt: Q7LFX5

  • Chr Location
    10q26.13; chr10:124007668-124093598 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    1 images
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit decreased litter size and abnormal bone marrow-derived mast cell morphology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1116
  • Tissues
    174
  • cDNA Data
    49
  • Literature Summary
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030930 Ensembl Gene Model | MGI Sequence Detail 81449 C57BL/6J ±  kb
transcript ENSMUST00000077472 Ensembl | MGI Sequence Detail 5041 Not Applicable  
polypeptide ENSMUSP00000076682 Ensembl | MGI Sequence Detail 561 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 51
    cDNA 49
    Primer pair 1
    Other 1

    Microarray probesets 6
References
more
  • Summaries
    All 40
    Developmental Gene Expression 11
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:343180 Ye J, et al., Silencing of tumoral carbohydrate sulfotransferase 15 reactivates lymph node pancreatic cancer T cells in mice. Eur J Immunol. 2023 Sep;53(9):e2250160
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory