Tmem250 MGI Mouse Gene Detail - MGI:1924939

Symbol

Tmem250
Name

transmembrane protein 250
Synonyms

C330006A16Rik

Feature Type

protein coding gene
IDs

MGI:1924939
NCBI Gene: 109299
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr2:26026819-26030518 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 2, 18.35 cM
Mapping Data

2 experiments

SNPs within 2kb

181 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1924939	protein coding gene	Chr2:26026819-26030533 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0005881	lincRNA gene	Chr2:24081965-24085648 (-)
A/J	MGP_AJ_G0005874	lincRNA gene	Chr2:23151559-23155248 (-)
AKR/J	MGP_AKRJ_G0005849	lincRNA gene	Chr2:23906844-23910532 (-)
BALB/cJ	MGP_BALBcJ_G0005853	lincRNA gene	Chr2:23264303-23268064 (-)
C3H/HeJ	MGP_C3HHeJ_G0005800	lincRNA gene	Chr2:23868351-23872041 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0006013	lincRNA gene	Chr2:24858361-24862056 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0005348	lincRNA gene	Chr2:22034757-22038481 (-)
CAST/EiJ	MGP_CASTEiJ_G0005736	lincRNA gene	Chr2:23737185-23740882 (-)
CBA/J	MGP_CBAJ_G0005785	lincRNA gene	Chr2:25693712-25700038 (-)
DBA/2J	MGP_DBA2J_G0005806	lincRNA gene	Chr2:22977590-22981287 (-)
FVB/NJ	MGP_FVBNJ_G0005832	lincRNA gene	Chr2:22727473-22731422 (-)
LP/J	MGP_LPJ_G0005885	lincRNA gene	Chr2:24020837-24024532 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0005819	lincRNA gene	Chr2:25857358-25861053 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0006010	lincRNA gene	Chr2:23870192-23873881 (-)
PWK/PhJ	MGP_PWKPhJ_G0005685	lincRNA gene	Chr2:22779027-22782760 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0005597	lincRNA gene	Chr2:23992201-23995920 (-)
WSB/EiJ	MGP_WSBEiJ_G0005789	lincRNA gene	Chr2:23970591-23974290 (-)

Human Ortholog

TMEM250, transmembrane protein 250

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TMEM250, transmembrane protein 250
Synonyms

C9orf69
Links

HGNC:31009

NCBI Gene ID: 90120

neXtProt AC: NX_H0YL14

UniProt: H0YL14
Chr Location

9q34.3

MGI Vertebrate Homology

Tmem250 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: TMEM250
Gene Tree

Tmem250

less

Phenotype Summary

2 phenotype references

All Mutations and Alleles

1
Gene trapped

1
Find Mice (IMSR)

0 strains or lines available

less

All GO Annotations

6
GO References

2

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

5

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase tmem250

less

All Sequences

36
RefSeq

4
UniProt

1
CCDS

CCDS89452.1

Ensembl

ENSMUSG00000087679 (Evidence)
NCBI Gene

109299

			Length	Strain/Species	Flank
genomic	109299	NCBI Gene Model \| MGI Sequence Detail	3700	C57BL/6J	± kb
transcript	NM_001256521	RefSeq \| MGI Sequence Detail	2474	C57BL/6
polypeptide	NP_001243450	RefSeq \| MGI Sequence Detail	139	C57BL/6

less

UniProt

1 Sequence
InterPro Domains

IPR041156 Protein of unknown function DUF5533

IPR053306 Transmembrane protein 250

less

All nucleic 5

cDNA 5

Microarray probesets 2

less

MGI:2139002, MGI:5897408

Summaries

All 21

Gene Ontology 2

Phenotypes 2
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Tmem250:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr23081	Chr2:26030544-26030566 (-)	-37 bp
Tssr23080	Chr2:26030480-26030542 (-)	7 bp
Tssr23079	Chr2:26030360-26030401 (-)	137 bp
Tssr23078	Chr2:26030301-26030356 (-)	189 bp
Tssr23077	Chr2:26028906-26028928 (-)	1,601 bp
Tssr23076	Chr2:26028288-26028290 (-)	2,229 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24