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Lhfpl3 Gene Detail
Summary
  • Symbol
    Lhfpl3
  • Name
    lipoma HMGIC fusion partner-like 3
  • Synonyms
    A930031L14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925076
    NCBI Gene: 269629
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:22951057-23480595 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 10.07 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    16576 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925076
 protein coding gene Chr5:22951052-23480595 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029328
 protein coding gene Chr5:20315709-20898451 (+)
A/J MGP_AJ_G0029293
 protein coding gene Chr5:19678984-20209296 (+)
AKR/J MGP_AKRJ_G0029244
 protein coding gene Chr5:20439445-21009443 (+)
BALB/cJ MGP_BALBcJ_G0029305
 protein coding gene Chr5:20141326-20694998 (+)
C3H/HeJ MGP_C3HHeJ_G0029024
 protein coding gene Chr5:20527106-21081088 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029758
 protein coding gene Chr5:21784174-22384982 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026996
 protein coding gene Chr5:17676434-18206337 (+)
CAST/EiJ MGP_CASTEiJ_G0028436
 protein coding gene Chr5:19819905-20382023 (+)
CBA/J MGP_CBAJ_G0028991
 protein coding gene Chr5:22093279-22683566 (+)
DBA/2J MGP_DBA2J_G0029143
 protein coding gene Chr5:19963684-20512587 (+)
FVB/NJ MGP_FVBNJ_G0029101
 protein coding gene Chr5:19364943-19903253 (+)
LP/J MGP_LPJ_G0029227
 protein coding gene Chr5:20721836-21289751 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029129
 protein coding gene Chr5:23289749-23888871 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029791
 protein coding gene Chr5:20032518-20616313 (+)
PWK/PhJ MGP_PWKPhJ_G0028159
 protein coding gene Chr5:18995300-19555858 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027992
 protein coding gene Chr5:19420715-19990349 (+)
WSB/EiJ MGP_WSBEiJ_G0028516
 protein coding gene Chr5:20130375-20712411 (+)



Homology
more
  • Human Ortholog
    LHFPL3, LHFPL tetraspan subfamily member 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LHFPL3, LHFPL tetraspan subfamily member 3
  • Synonyms
    LHFPL4
  • Links
    NCBI Gene ID: 375612
    neXtProt AC: NX_Q86UP9
    UniProt: Q86UP9

  • Chr Location
    7q22.2-q22.3
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    4 involving Lhfpl3
  • Find Mice (IMSR)
    24 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    780
  • Tissues
    46
  • cDNA Data
    6
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000106379 Ensembl Gene Model | MGI Sequence Detail 529539 C57BL/6J ±  kb
transcript ENSMUST00000197992 Ensembl | MGI Sequence Detail 3115 Not Applicable  
polypeptide ENSMUSP00000143576 Ensembl | MGI Sequence Detail 228 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 6
    Primer pair 2

    Microarray probesets 2
References
more
  • Summaries
    All 38
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 2
    Phenotypes 14
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:340982 Qiu X, et al., The tetraspan LHFPL5 is critical to establish maximal force sensitivity of the mechanotransduction channel of cochlear hair cells. Cell Rep. 2023 Mar 28;42(3):112245
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory