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Scaf8 Gene Detail
Summary
  • Symbol
    Scaf8
  • Name
    SR-related CTD-associated factor 8
  • Synonyms
    A630086M08Rik, A930036P18Rik, mKIAA1116, Rbm16
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925212
    NCBI Gene: 106583
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:3165247-3249134 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 1.96 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1635 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925212
 protein coding gene Chr17:3165247-3249134 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0023068
 protein coding gene Chr17:161666-263978 (+)
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0023516
 protein coding gene Chr17:156312-289644 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021016
 protein coding gene Chr17:25339-106478 (+)
CAST/EiJ MGP_CASTEiJ_G0022348
 protein coding gene Chr17:147833-211478 (+)
CBA/J MGP_CBAJ_G0022797
 protein coding gene Chr17:76951-204816 (+)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0022906
 protein coding gene Chr17:54566-146584 (+)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0023533
 protein coding gene Chr17:66118-167696 (+)
PWK/PhJ MGP_PWKPhJ_G0022093
 protein coding gene Chr17:31568-132189 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0022399
 protein coding gene Chr17:71261-179940 (+)



Homology
more
  • Human Ortholog
    SCAF8, SR-related CTD associated factor 8
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SCAF8, SR-related CTD associated factor 8
  • Synonyms
    RBM16
  • Links
    NCBI Gene ID: 22828
    neXtProt AC: NX_Q9UPN6
    UniProt: Q9UPN6

  • Chr Location
    6q25.2; chr6:154733378-154834244 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    728
  • Tissues
    22
  • cDNA Data
    20
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 106583 NCBI Gene Model | MGI Sequence Detail 83888 C57BL/6J ±  kb
transcript NM_134123 RefSeq | MGI Sequence Detail 4892 C57BL/6  
polypeptide Q6DID3 UniProt | EBI | MGI Sequence Detail 1268 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 22
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146750, MGI:2146856, MGI:2146860, MGI:2146966, MGI:2443128
References
more
  • Summaries
    All 44
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 14
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:337878 Xing Z, et al., Dissection of a Down syndrome-associated trisomy to separate the gene dosage-dependent and -independent effects of an extra chromosome. Hum Mol Genet. 2023 Jun 19;32(13):2205-2218
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory