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Spata31 Gene Detail
Summary
  • Symbol
    Spata31
  • Name
    spermatogenesis associated 31
  • Synonyms
    4930458L03Rik, Fam75a, Spata31a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925374
    NCBI Gene: 78124
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:65065220-65071008 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 34.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    214 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925374
 protein coding gene Chr13:65065220-65071009 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020682
 protein coding gene Chr13:64947627-64953486 (+)
A/J MGP_AJ_G0020636
 protein coding gene Chr13:62582185-62588018 (+)
AKR/J MGP_AKRJ_G0020613
 protein coding gene Chr13:64654602-64660459 (+)
BALB/cJ MGP_BALBcJ_G0020634
 protein coding gene Chr13:63009972-63015811 (+)
C3H/HeJ MGP_C3HHeJ_G0020429
 protein coding gene Chr13:64186984-64192859 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021070
 protein coding gene Chr13:67053249-67059027 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018646
 protein coding gene Chr13:60225206-60230425 (+)
CAST/EiJ MGP_CASTEiJ_G0019946
 protein coding gene Chr13:64206188-64212353 (+)
CBA/J MGP_CBAJ_G0020389
 protein coding gene Chr13:69626204-69632085 (+)
DBA/2J MGP_DBA2J_G0020514
 protein coding gene Chr13:62421477-62427338 (+)
FVB/NJ MGP_FVBNJ_G0020493
 protein coding gene Chr13:61508448-61514291 (+)
LP/J MGP_LPJ_G0020588
 protein coding gene Chr13:65234696-65240556 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020522
 protein coding gene Chr13:68561331-68568213 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021112
 protein coding gene Chr13:63977591-63984053 (+)
PWK/PhJ MGP_PWKPhJ_G0019700
 protein coding gene Chr13:61972353-61978261 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019526
 protein coding gene Chr13:62165681-62171552 (+)
WSB/EiJ MGP_WSBEiJ_G0020006
 protein coding gene Chr13:64465879-64472768 (+)



Homology
more
  • Human Ortholog
    SPATA31A1, SPATA31 subfamily A member 1
  • Vertebrate Orthologs
    8
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPATA31A1, SPATA31 subfamily A member 1
  • Synonyms
    C9orf36, C9orf36A, FAM75A1, FAM75A2, SPATA31A2
  • Links
    NCBI Gene ID: 647060
    UniProt: Q5TZJ5

  • Chr Location
    9p12; chr9:39355667-39361962 (+)  GRCh38
  • Human Ortholog
    SPATA31A3, SPATA31 subfamily A member 3
  • Synonyms
    FAM75A3
  • Links
    NCBI Gene ID: 727830
    neXtProt AC: NX_Q5VYP0
    UniProt: Q5VYP0

  • Chr Location
    9q21.11; chr9:66986304-66992550 (-)  GRCh38
  • Human Ortholog
    SPATA31A5, SPATA31 subfamily A member 5
  • Synonyms
    FAM75A5
  • Links
    NCBI Gene ID: 727905
    neXtProt AC: NX_Q5VU36
    UniProt: Q5VU36

  • Chr Location
    9q12; chr9:60914372-60920653 (+)  GRCh38
  • Human Ortholog
    SPATA31A6, SPATA31 subfamily A member 6
  • Synonyms
    FAM75A6
  • Links
    NCBI Gene ID: 389730
    neXtProt AC: NX_Q5VVP1
    UniProt: Q5VVP1

  • Chr Location
    9p11.2; chr9:42183659-42189887 (+)  GRCh38
  • Human Ortholog
    SPATA31A7, SPATA31 subfamily A member 7
  • Synonyms
    AEP1, C9orf36, C9orf36A, FAM75A4, FAM75A7, SPATA31A4
  • Links
    NCBI Gene ID: 26165
    neXtProt AC: NX_Q8IWB4
    UniProt: Q8IWB4

  • Chr Location
    9q12; chr9:61190036-61196280 (+)  GRCh38
  • Human Ortholog
    SPATA31C1, SPATA31 subfamily C member 1
  • Synonyms
    FAM75C1, SPATA31C2
  • Links
    NCBI Gene ID: 441452
    neXtProt AC: NX_P0DKV0
    UniProt: P0DKV0

  • Chr Location
    9q22.1; chr9:87913936-87923657 (+)  GRCh38
  • Human Ortholog
    SPATA31C2, SPATA31 subfamily C member 2
  • Synonyms
    FAM75C2
  • Links
    NCBI Gene ID: 645961
    neXtProt AC: NX_B4DYI2
    UniProt: B4DYI2

  • Chr Location
    9q22.1
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice with loss of expression in the gonads display male infertility with oligoteratozoospermia, marked reduction in spermatid numbers, and premature release of germ cells.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000056223 Ensembl Gene Model | MGI Sequence Detail 5789 C57BL/6J ±  kb
    transcript ENSMUST00000070216 Ensembl | MGI Sequence Detail 3232 Not Applicable  
    polypeptide ENSMUSP00000097025 Ensembl | MGI Sequence Detail 1014 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR039509 SPATA31
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 1
    References
    more
    • Summaries
      All 24
      Gene Ontology 3
      Phenotypes 6
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:296898 Tonelli Gombalova Z, et al., Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species. J Comp Neurol. 2020 Oct 15;528(15):2523-2550
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory