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Lsm6 Gene Detail
Summary
  • Symbol
    Lsm6
  • Name
    LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
  • Synonyms
    1500031N17Rik, 2410088K19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925901
    NCBI Gene: 78651
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:79531494-79547769 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 37.22 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    540 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925901
 protein coding gene Chr8:79531494-79547781 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033808
 protein coding gene Chr8:79448037-79465900 (-)
A/J MGP_AJ_G0033790
 protein coding gene Chr8:76272347-76288703 (-)
AKR/J MGP_AKRJ_G0033717
 protein coding gene Chr8:78566025-78582295 (-)
BALB/cJ MGP_BALBcJ_G0033784
 protein coding gene Chr8:76381765-76398212 (-)
C3H/HeJ MGP_C3HHeJ_G0033493
 protein coding gene Chr8:79186353-79202968 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034304
 protein coding gene Chr8:82489138-82513998 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031245
 protein coding gene Chr8:70367742-70383936 (-)
CAST/EiJ MGP_CASTEiJ_G0032824
 protein coding gene Chr8:78526611-78542857 (-)
CBA/J MGP_CBAJ_G0033472
 protein coding gene Chr8:85422083-85438292 (-)
DBA/2J MGP_DBA2J_G0033625
 protein coding gene Chr8:75966979-75984813 (-)
FVB/NJ MGP_FVBNJ_G0033570
 protein coding gene Chr8:74958285-74975092 (-)
LP/J MGP_LPJ_G0033715
 protein coding gene Chr8:79536914-79553187 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033613
 protein coding gene Chr8:87993810-88010420 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034321
 protein coding gene Chr8:78587283-78603699 (-)
PWK/PhJ MGP_PWKPhJ_G0032527
 protein coding gene Chr8:75244971-75261361 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032365
 protein coding gene Chr8:77397912-77414249 (-)
WSB/EiJ MGP_WSBEiJ_G0032937
 protein coding gene Chr8:78913941-78930198 (-)



Homology
more
  • Human Ortholog
    LSM6, LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LSM6, LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
  • Synonyms
    YDR378C
  • Links
    NCBI Gene ID: 11157
    neXtProt AC: NX_P62312
    UniProt: P62312

  • Chr Location
    4q31.22; chr4:146175703-146200000 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Genomic Mutations
    1 involving Lsm6
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    7 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    729
  • Tissues
    23
  • cDNA Data
    51
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031683 Ensembl Gene Model | MGI Sequence Detail 16276 C57BL/6J ±  kb
transcript ENSMUST00000051867 Ensembl | MGI Sequence Detail 2107 Not Applicable  
polypeptide ENSMUSP00000049722 Ensembl | MGI Sequence Detail 80 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 52
    cDNA 51
    Primer pair 1

    Microarray probesets 9
Other
Accession IDs
less
MGI:1916265, MGI:2142614
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory