Ccdc166 MGI Mouse Gene Detail - MGI:1925902 - coiled-coil domain containing 166

Symbol

Ccdc166
Name

coiled-coil domain containing 166
Synonyms

2410075B13Rik

Feature Type

protein coding gene
IDs

MGI:1925902
NCBI Gene: 223648
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr15:75851721-75854134 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 15, 35.18 cM
Mapping Data

3 experiments

SNPs within 2kb

152 from dbSNP Build 142
Strain Annotations

17

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1925902	protein coding gene	Chr15:75851721-75854304 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0021969	protein coding gene	Chr15:76032131-76034714 (-)
A/J	MGP_AJ_G0021927	protein coding gene	Chr15:73262303-73264886 (-)
AKR/J	MGP_AKRJ_G0021910	protein coding gene	Chr15:75244494-75247077 (-)
BALB/cJ	MGP_BALBcJ_G0021936	protein coding gene	Chr15:73282423-73285006 (-)
C3H/HeJ	MGP_C3HHeJ_G0021708	protein coding gene	Chr15:75301062-75303645 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0022376	protein coding gene	Chr15:78869926-78872509 (-)
CAROLI/EiJ	no annotation
CAST/EiJ	MGP_CASTEiJ_G0021227	protein coding gene	Chr15:76089228-76091811 (-)
CBA/J	MGP_CBAJ_G0021675	protein coding gene	Chr15:81381389-81383972 (-)
DBA/2J	MGP_DBA2J_G0021800	protein coding gene	Chr15:72792850-72795433 (-)
FVB/NJ	MGP_FVBNJ_G0021781	protein coding gene	Chr15:71843322-71845905 (-)
LP/J	MGP_LPJ_G0021871	protein coding gene	Chr15:76111298-76113881 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0021805	protein coding gene	Chr15:86684434-86687017 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0022396	protein coding gene	Chr15:75492182-75494765 (-)
PWK/PhJ	MGP_PWKPhJ_G0020968	protein coding gene	Chr15:72935798-72938380 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0020807	protein coding gene	Chr15:75210132-75212708 (-)
WSB/EiJ	MGP_WSBEiJ_G0021279	protein coding gene	Chr15:75575115-75577698 (-)

Human Ortholog

CCDC166, coiled-coil domain containing 166

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CCDC166, coiled-coil domain containing 166
Links

HGNC:41910

NCBI Gene ID: 100130274

neXtProt AC: NX_P0CW27

UniProt: P0CW27
Chr Location

8q24.3; chr8:143706694-143708109 (-) GRCh38

MGI Vertebrate Homology

Ccdc166 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: CCDC166
Gene Tree

Ccdc166

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References

1 with disease annotations

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
27 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

7
Chemically induced (other)

3
Endonuclease-mediated

2
Radiation induced

2
Genomic Mutations

5 involving Ccdc166
Find Mice (IMSR)

13 strains or lines available

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Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

708
Tissues

2
cDNA Data

8
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

40
RefSeq

4
UniProt

3
CCDS

CCDS59620.1, CCDS59621.1

Ensembl

ENSMUSG00000098176 (Evidence)
NCBI Gene

223648

			Length	Strain/Species	Flank
genomic	223648	NCBI Gene Model \| MGI Sequence Detail	2414	C57BL/6J	± kb
transcript	NM_001163518	RefSeq \| MGI Sequence Detail	2414	C57BL/6
polypeptide	NP_666171	RefSeq \| MGI Sequence Detail	449	C57BL/6

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UniProt

3 Sequences
InterPro Domains

IPR032777 Domain of unknown function DUF4515

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All nucleic 8

cDNA 8

Microarray probesets 5

Summaries

All 47

Developmental Gene Expression 1

Diseases 1

Phenotypes 27
Earliest

J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Ccdc166:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr134892	Chr15:75853793-75853849 (-)	313 bp
Tssr134891	Chr15:75853672-75853687 (-)	454 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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