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Cacul1 Gene Detail
Summary
  • Symbol
    Cacul1
  • Name
    CDK2 associated, cullin domain 1
  • Synonyms
    2700078E11Rik, 2810417M16Rik, 9830127L17Rik, D130033C15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926082
    NCBI Gene: 78832
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:60513143-60569420 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 56.52 cM, cytoband D3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1241 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926082
 protein coding gene Chr19:60513134-60569463 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025293
 protein coding gene Chr19:61102370-61165618 (-)
A/J MGP_AJ_G0025269
 protein coding gene Chr19:58124560-58183493 (-)
AKR/J MGP_AKRJ_G0025238
 protein coding gene Chr19:59935952-59995600 (-)
BALB/cJ MGP_BALBcJ_G0025264
 protein coding gene Chr19:58193517-58256865 (-)
C3H/HeJ MGP_C3HHeJ_G0025024
 protein coding gene Chr19:60190916-60251414 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025707
 protein coding gene Chr19:62568713-62630017 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023119
 protein coding gene Chr19:56959225-57019223 (-)
CAST/EiJ MGP_CASTEiJ_G0024489
 protein coding gene Chr19:60277679-60337764 (-)
CBA/J MGP_CBAJ_G0025004
 protein coding gene Chr19:65617771-65693137 (-)
DBA/2J MGP_DBA2J_G0025136
 protein coding gene Chr19:57876331-57938106 (-)
FVB/NJ MGP_FVBNJ_G0025097
 protein coding gene Chr19:57581766-57645419 (-)
LP/J MGP_LPJ_G0025222
 protein coding gene Chr19:60943718-61002277 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025130
 protein coding gene Chr19:64801153-64864927 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025765
 protein coding gene Chr19:60188647-60247465 (-)
PWK/PhJ MGP_PWKPhJ_G0024237
 protein coding gene Chr19:57861925-57919244 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024040
 protein coding gene Chr19:58825676-58887222 (-)
WSB/EiJ MGP_WSBEiJ_G0024559
 protein coding gene Chr19:60287315-60351079 (-)



Homology
more
  • Human Ortholog
    CACUL1, CDK2 associated cullin domain 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CACUL1, CDK2 associated cullin domain 1
  • Synonyms
    C10orf46, CAC1
  • Links
    NCBI Gene ID: 143384
    neXtProt AC: NX_Q86Y37
    UniProt: Q86Y37

  • Chr Location
    10q26.11; chr10:118674167-118755249 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 78832 NCBI Gene Model | MGI Sequence Detail 56278 C57BL/6J ±  kb
transcript NM_030197 RefSeq | MGI Sequence Detail 5740 C57BL/6  
polypeptide Q8R0X2 UniProt | EBI | MGI Sequence Detail 377 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000032325 CDK2-associated and cullin domain-containing protein 1
    (term hierarchy)
  • InterPro Domains
    IPR042652 CDK2-associated and cullin domain-containing protein 1
    IPR001373 Cullin, N-terminal
    IPR016159 Cullin repeat-like-containing domain superfamily
  • GlyGen
    Q8R0X2 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 8
Other
Accession IDs
less
MGI:1916517, MGI:2147544, MGI:2444038, MGI:2445103
References
more
  • Summaries
    All 32
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory