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Abraxas2 Gene Detail
Summary
  • Symbol
    Abraxas2
  • Name
    BRISC complex subunit
  • Synonyms
    C430003P19Rik, Fam175b, KIAA0157
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926116
    NCBI Gene: 109359
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:132460954-132486840 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 76.32 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    699 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926116
 protein coding gene Chr7:132460954-132486843 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033117
 protein coding gene Chr7:137569589-137595882 (+)
A/J MGP_AJ_G0033099
 protein coding gene Chr7:133779379-133805086 (+)
AKR/J MGP_AKRJ_G0033031
 protein coding gene Chr7:137342320-137370644 (+)
BALB/cJ MGP_BALBcJ_G0033100
 protein coding gene Chr7:133462061-133488303 (+)
C3H/HeJ MGP_C3HHeJ_G0032814
 protein coding gene Chr7:137181884-137208672 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033611
 protein coding gene Chr7:142802254-142829387 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030582
 protein coding gene Chr7:135059940-135086689 (+)
CAST/EiJ MGP_CASTEiJ_G0032143
 protein coding gene Chr7:129047022-129122281 (+)
CBA/J MGP_CBAJ_G0032787
 protein coding gene Chr7:147638380-147671687 (+)
DBA/2J MGP_DBA2J_G0032939
 protein coding gene Chr7:131792251-131821680 (+)
FVB/NJ MGP_FVBNJ_G0032892
 protein coding gene Chr7:131631806-131657369 (+)
LP/J MGP_LPJ_G0033033
 protein coding gene Chr7:139087454-139113982 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032924
 protein coding gene Chr7:148557103-148583600 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033631
 protein coding gene Chr7:136338235-136370496 (+)
PWK/PhJ MGP_PWKPhJ_G0031849
 protein coding gene Chr7:124769116-124841903 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031696
 protein coding gene Chr7:123123498-123149394 (+)
WSB/EiJ MGP_WSBEiJ_G0032255
 protein coding gene Chr7:137241089-137267780 (+)



Homology
more
  • Human Ortholog
    ABRAXAS2, abraxas 2, BRISC complex subunit
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ABRAXAS2, abraxas 2, BRISC complex subunit
  • Synonyms
    ABRO1, FAM175B, KIAA0157
  • Links
    NCBI Gene ID: 23172
    neXtProt AC: NX_Q15018
    UniProt: Q15018

  • Chr Location
    10q26.13; chr10:124801819-124836667 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    44
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    12
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030965 Ensembl Gene Model | MGI Sequence Detail 25887 C57BL/6J ±  kb
transcript ENSMUST00000084497 Ensembl | MGI Sequence Detail 2892 Not Applicable  
polypeptide ENSMUSP00000081541 Ensembl | MGI Sequence Detail 424 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
Other
Accession IDs
less
MGI:2141844, MGI:2142066, MGI:5896593
References
more
  • Summaries
    All 44
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory