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Ftx Gene Detail
Summary
  • Symbol
    Ftx
  • Name
    Ftx transcript, Xist regulator, non-protein coding
  • Synonyms
    B230206F22Rik, Thcytx
  • Feature Type
    lncRNA gene
  • IDs
    MGI:1926128
    NCBI Gene: 78878
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:102604516-102667360 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 46.21 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    642 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926128
 lncRNA gene ChrX:102604513-102667396 (-)
129S1/SvImJ MGP_129S1SvImJ_G0007556
 lincRNA gene ChrX:100225678-100291891 (-)
A/J MGP_AJ_G0007555
 lincRNA gene ChrX:100150356-100212823 (-)
AKR/J MGP_AKRJ_G0007525
 lincRNA gene ChrX:103173648-103240819 (-)
BALB/cJ MGP_BALBcJ_G0007529
 lincRNA gene ChrX:98940546-99011123 (-)
C3H/HeJ MGP_C3HHeJ_G0007476
 lincRNA gene ChrX:100678618-100747043 (-)
C57BL/6NJ MGP_C57BL6NJ_G0007702
 lincRNA gene ChrX:103179635-103250761 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0006879
 lincRNA gene ChrX:97781635-97843452 (-)
CAST/EiJ MGP_CASTEiJ_G0007378
 lincRNA gene ChrX:84950981-85016804 (-)
CBA/J MGP_CBAJ_G0007457
 lincRNA gene ChrX:106369017-106447137 (-)
DBA/2J MGP_DBA2J_G0007482
 lincRNA gene ChrX:99389759-99453336 (-)
FVB/NJ MGP_FVBNJ_G0007498
 lincRNA gene ChrX:98694110-98760931 (-)
LP/J MGP_LPJ_G0007562
 lincRNA gene ChrX:101231738-101307110 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0007478
 lincRNA gene ChrX:111035187-111101171 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0007705
 lincRNA gene ChrX:99898374-99966631 (-)
PWK/PhJ MGP_PWKPhJ_G0007316
 lincRNA gene ChrX:82530343-82594035 (-)
SPRET/EiJ MGP_SPRETEiJ_G0007220
 lincRNA gene ChrX:85652180-85726603 (-)
WSB/EiJ MGP_WSBEiJ_G0007439
 lincRNA gene ChrX:98621700-98687921 (-)



Homology
more
  • Human Ortholog
    FTX, FTX transcript, XIST regulator
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FTX, FTX transcript, XIST regulator
  • Synonyms
    LINC00182, MIR374AHG, NCRNA00182
  • Links
    NCBI Gene ID: 100302692

  • Chr Location
    Xq13.2; chrX:73940435-74293574 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 3 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit partially abnormal X-inactivation that results in microphthalmia in some homozygous and heterozygous female mice.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    717
  • Tissues
    4
  • cDNA Data
    6
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      66
    • RefSeq
      2
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 78878 NCBI Gene Model | MGI Sequence Detail 62845 C57BL/6J ±  kb
    transcript NR_028380 RefSeq | MGI Sequence Detail 4387 ZRU/MplStud  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 6
      Primer pair 3
    Other
    Accession IDs
    less
    MGI:2148043
    References
    more
    • Summaries
      All 20
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:293830 Collombet S, et al., Parental-to-embryo switch of chromosome organization in early embryogenesis. Nature. 2020 Apr;580(7801):142-146
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory