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Mrpl19 Gene Detail
Summary
  • Symbol
    Mrpl19
  • Name
    mitochondrial ribosomal protein L19
  • Synonyms
    9030416F12Rik, D6Ertd157e, MRP-L15, RLX1, Rpml15
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926274
    NCBI Gene: 56284
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:81934832-81942939 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 35.81 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    409 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926274
 protein coding gene Chr6:81934807-81942939 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030902
 protein coding gene Chr6:82926511-82936395 (-)
A/J MGP_AJ_G0030871
 protein coding gene Chr6:79735331-79743410 (-)
AKR/J MGP_AKRJ_G0030799
 protein coding gene Chr6:82009487-82017596 (-)
BALB/cJ MGP_BALBcJ_G0030881
 protein coding gene Chr6:79760621-79768970 (-)
C3H/HeJ MGP_C3HHeJ_G0030829
 protein coding gene Chr6:102317725-102327937 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031341
 protein coding gene Chr6:85166747-85176781 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028527
 protein coding gene Chr6:78164866-78172917 (-)
CAST/EiJ MGP_CASTEiJ_G0029990
 protein coding gene Chr6:82024773-82032724 (-)
CBA/J MGP_CBAJ_G0030568
 protein coding gene Chr6:88555565-88565359 (-)
DBA/2J MGP_DBA2J_G0030721
 protein coding gene Chr6:79035784-79044662 (-)
FVB/NJ MGP_FVBNJ_G0030674
 protein coding gene Chr6:78291987-78300072 (-)
LP/J MGP_LPJ_G0030800
 protein coding gene Chr6:82908797-82919014 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030710
 protein coding gene Chr6:92882728-92892384 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031365
 protein coding gene Chr6:81856872-81864787 (-)
PWK/PhJ MGP_PWKPhJ_G0029705
 protein coding gene Chr6:77951774-77960241 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029533
 protein coding gene Chr6:80719933-80727943 (-)
WSB/EiJ MGP_WSBEiJ_G0030071
 protein coding gene Chr6:82289186-82299175 (-)



Homology
more
  • Human Ortholog
    MRPL19, mitochondrial ribosomal protein L19
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL19, mitochondrial ribosomal protein L19
  • Synonyms
    bL19m, L15mt, L19mt, MRP-L15, MRPL15, MRP-L19, RLX1, RPML15
  • Links
    NCBI Gene ID: 9801
    neXtProt AC: NX_P49406
    UniProt: P49406

  • Chr Location
    2p12; chr2:75646783-75690851 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    13
  • cDNA Data
    18
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030045 Ensembl Gene Model | MGI Sequence Detail 8108 C57BL/6J ±  kb
transcript ENSMUST00000032124 Ensembl | MGI Sequence Detail 5000 Not Applicable  
polypeptide ENSMUSP00000032124 Ensembl | MGI Sequence Detail 292 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000010581 large ribosomal subunit protein bL19m
    (term hierarchy)
  • InterPro Domains
    IPR001857 Large ribosomal subunit protein bL19
    IPR038657 Large ribosomal subunit protein bL19 superfamily
    IPR008991 Translation protein SH3-like domain superfamily
Molecular
Reagents
less
  • All nucleic 21
    cDNA 19
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:1098795, MGI:1915232
References
more
  • Summaries
    All 42
    Developmental Gene Expression 1
    Gene Ontology 9
    Phenotypes 9
  • Earliest
    J:64919 Graack HR, et al., Identification of mammalian mitochondrial ribosomal proteins (MRPs) by N-terminal sequencing of purified bovine MRPs and comparison to data bank sequences: the large subribosomal particle. Biochemistry. 1999 Dec 14;38(50):16569-77
  • Latest
    J:330636 Iwata S, et al., An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain. G3 (Bethesda). 2021;11(8)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory