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B4galt5 Gene Detail
Summary
  • Symbol
    B4galt5
  • Name
    UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
  • Synonyms
    9430078I07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927169
    NCBI Gene: 56336
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:167140364-167191103 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 87.22 cM, cytoband H3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1186 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927169
 protein coding gene Chr2:167140364-167191155 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026911
 protein coding gene Chr2:173018188-173070878 (-)
A/J MGP_AJ_G0026878
 protein coding gene Chr2:165902310-165954028 (-)
AKR/J MGP_AKRJ_G0026849
 protein coding gene Chr2:170847845-170900447 (-)
BALB/cJ MGP_BALBcJ_G0026887
 protein coding gene Chr2:166253749-166304758 (-)
C3H/HeJ MGP_C3HHeJ_G0026629
 protein coding gene Chr2:171215706-171267351 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027334
 protein coding gene Chr2:178056840-178112303 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024705
 protein coding gene Chr2:159226499-159277214 (-)
CAST/EiJ MGP_CASTEiJ_G0026087
 protein coding gene Chr2:171679315-171732665 (-)
CBA/J MGP_CBAJ_G0026606
 protein coding gene Chr2:184577896-184636996 (-)
DBA/2J MGP_DBA2J_G0026744
 protein coding gene Chr2:165021957-165072756 (-)
FVB/NJ MGP_FVBNJ_G0026710
 protein coding gene Chr2:163532461-163583565 (-)
LP/J MGP_LPJ_G0026845
 protein coding gene Chr2:173037154-173093942 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026729
 protein coding gene Chr2:187983626-188034954 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027391
 protein coding gene Chr2:170768345-170823878 (-)
PWK/PhJ MGP_PWKPhJ_G0025824
 protein coding gene Chr2:164674446-164727092 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025625
 protein coding gene Chr2:169698769-169751052 (-)
WSB/EiJ MGP_WSBEiJ_G0026160
 protein coding gene Chr2:171687239-171738053 (-)



Homology
more
  • Human Ortholog
    B4GALT5, beta-1,4-galactosyltransferase 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    B4GALT5, beta-1,4-galactosyltransferase 5
  • Synonyms
    B4Gal-T5, beta4Gal-T5, BETA4-GALT-IV, beta4GalT-V, gt-V
  • Links
    NCBI Gene ID: 9334
    neXtProt AC: NX_O43286
    UniProt: O43286

  • Chr Location
    20q13.13; chr20:49632945-49713878 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 2 alleles in 2 genetic backgrounds
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutation of this gene results in lethality before weaning. Heterozygous mutant mice exhibit increased anxiety-like response.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    891
  • Tissues
    130
  • cDNA Data
    12
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000017929 Ensembl Gene Model | MGI Sequence Detail 50740 C57BL/6J ±  kb
    transcript ENSMUST00000109221 Ensembl | MGI Sequence Detail 4210 Not Applicable  
    polypeptide ENSMUSP00000104844 Ensembl | MGI Sequence Detail 388 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 12
      Primer pair 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1924610, MGI:2139281, MGI:2139367
    References
    more
    • Summaries
      All 53
      Developmental Gene Expression 3
      Gene Ontology 13
      Phenotypes 17
    • Earliest
      J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory