Tl Gene Detail

Summary

• Symbol
  Tl
• Name
  brachyury-like

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:1927233
  NCBI Gene: 109651
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 17, Syntenic
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotypes from 1 allele in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  0 strains or lines available

Mice homozygous for a spontaneous mutation show complete prenatal lethality. Heterozygous mutant mice exhibit a short tail and skeletal defects.

Sequences &
Gene Models

• NCBI Gene
  109651

References

• Summaries
  All 3

  Phenotypes 1
• Earliest
  J:190269 Pereira LA, et al., Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity. PLoS One. 2011;6(12):e28394