Sap30bp MGI Mouse Gene Detail - MGI:1927479

Symbol

Sap30bp
Name

SAP30 binding protein
Synonyms

2700016D05Rik, Hcngp

Feature Type

protein coding gene
IDs

MGI:1927479
NCBI Gene: 57230
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr11:115824477-115857547 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 80.91 cM, cytoband E2
Mapping Data

3 experiments

SNPs within 2kb

919 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1927479	protein coding gene	Chr11:115824108-115857551 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0019407	protein coding gene	Chr11:120011015-120046892 (+)
A/J	MGP_AJ_G0019376	protein coding gene	Chr11:114762275-114796233 (+)
AKR/J	MGP_AKRJ_G0019346	protein coding gene	Chr11:118191779-118226668 (+)
BALB/cJ	MGP_BALBcJ_G0019350	protein coding gene	Chr11:115177140-115212520 (+)
C3H/HeJ	MGP_C3HHeJ_G0019156	protein coding gene	Chr11:118538090-118573513 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0019800	protein coding gene	Chr11:123670925-123704001 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017423	protein coding gene	Chr11:111785810-111819260 (+)
CAST/EiJ	MGP_CASTEiJ_G0018711	protein coding gene	Chr11:119882168-119919796 (+)
CBA/J	MGP_CBAJ_G0019128	protein coding gene	Chr11:128564240-128600556 (+)
DBA/2J	MGP_DBA2J_G0019239	protein coding gene	Chr11:114184417-114218230 (+)
FVB/NJ	MGP_FVBNJ_G0019231	protein coding gene	Chr11:113693806-113728028 (+)
LP/J	MGP_LPJ_G0019309	protein coding gene	Chr11:120390117-120426606 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019264	protein coding gene	Chr11:127676554-127709484 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019838	protein coding gene	Chr11:118842045-118875969 (+)
PWK/PhJ	MGP_PWKPhJ_G0018475	protein coding gene	Chr11:115501794-115538553 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0018268	protein coding gene	Chr11:118593988-118628291 (+)
WSB/EiJ	MGP_WSBEiJ_G0018763	protein coding gene	Chr11:118806264-118841051 (+)

Human Ortholog

SAP30BP, SAP30 binding protein

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SAP30BP, SAP30 binding protein
Synonyms

HCNGP, HTRG, HTRP
Links

HGNC:30785

NCBI Gene ID: 29115

neXtProt AC: NX_Q9UHR5

UniProt: Q9UHR5
Chr Location

17q25.1; chr17:75667251-75708062 (+) GRCh38

MGI Vertebrate Homology

Sap30bp stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: SAP30BP
Gene Tree

Sap30bp

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
12 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

101
Endonuclease-mediated

4
Gene trapped

94
Targeted

2
Transgenic

1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

42 strains or lines available

Mice homozygous for a transgenic gene disruption exhibit anemia at E16.

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All GO Annotations

11
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

742
Tissues

19
cDNA Data

9
Literature Summary

4

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase sap30bp

ZFIN sap30bp

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All Sequences

45
RefSeq

7
UniProt

1
CCDS

CCDS25651.1

Ensembl

ENSMUSG00000020755 (Evidence)
NCBI Gene

57230

			Length	Strain/Species	Flank
genomic	57230	NCBI Gene Model \| MGI Sequence Detail	33071	C57BL/6J	± kb
transcript	NR_184577	RefSeq \| MGI Sequence Detail	3480	C57BL/6
polypeptide	Q02614	UniProt \| EBI \| MGI Sequence Detail	308	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000014449 SAP30-binding protein

(term hierarchy)
InterPro Domains

IPR012479 SAP30-binding protein
GlyGen

Q02614 10 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (8 sites)

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All nucleic 9

cDNA 9

Microarray probesets 5

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MGI:1917277

Summaries

All 41

Developmental Gene Expression 4

Gene Ontology 5

Phenotypes 12
Earliest

J:3174 Palmer DB, et al., The chromatin structure of the mouse beta-2-microglobulin locus. Differentiation. 1992 Nov;51(3):201-7
Latest

J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Sap30bp:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr105922	Chr11:115824455-115824495 (+)	-2 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24