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Svs3a Gene Detail
Summary
  • Symbol
    Svs3a
  • Name
    seminal vesicle secretory protein 3A
  • Synonyms
    9530026M05Rik, Svp-3, Svp3, Svs3, SVS III
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927635
    NCBI Gene: 64335
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164131188-164133420 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 85.07 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    235 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927635
 protein coding gene Chr2:164131187-164133420 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026844
 protein coding gene Chr2:169678505-169709297 (+)
A/J MGP_AJ_G0026811
 protein coding gene Chr2:162814222-162816693 (+)
AKR/J MGP_AKRJ_G0026781
 protein coding gene Chr2:167599534-167604708 (-)
BALB/cJ MGP_BALBcJ_G0026820
 protein coding gene Chr2:163155845-163157758 (+)
C3H/HeJ MGP_C3HHeJ_G0026561
 protein coding gene Chr2:167954678-167961102 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027268
 protein coding gene Chr2:174626763-174631669 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024638
 protein coding gene Chr2:156192331-156194445 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0026538
 protein coding gene Chr2:180917399-180953548 (+)
DBA/2J MGP_DBA2J_G0026676
 protein coding gene Chr2:161948180-161951214 (-)
FVB/NJ MGP_FVBNJ_G0026642
 protein coding gene Chr2:160360682-160392844 (+)
LP/J MGP_LPJ_G0026779
 protein coding gene Chr2:169750491-169751615 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0027324
 protein coding gene Chr2:167546201-167548114 (+)
PWK/PhJ MGP_PWKPhJ_G0025756
 protein coding gene Chr2:161527213-161531827 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025566
 protein coding gene Chr2:166603385-166604460 (+)
WSB/EiJ MGP_WSBEiJ_G0026093
 protein coding gene Chr2:168405735-168407624 (+)



Homology
more
  • Human Ortholog
    SEMG1, semenogelin 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SEMG1, semenogelin 1
  • Synonyms
    CT103, dJ172H20.2, SEMG, SGI
  • Links
    NCBI Gene ID: 6406
    neXtProt AC: NX_P04279
    UniProt: P04279

  • Chr Location
    20q13.12; chr20:45207033-45209768 (+)  GRCh38
  • Human Ortholog
    SEMG2, semenogelin 2
  • Synonyms
    SGII
  • Links
    NCBI Gene ID: 6407
    neXtProt AC: NX_Q02383
    UniProt: Q02383

  • Chr Location
    20q13.12; chr20:45221373-45224458 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
At this locus, the a allele determines a slow anodally migrating enzyme band and occurs in the B10.AKM/Sn strain; the b allele determines a faster band and occurs in AKR.M/Sn, C3H/He and C57BL/10Orl strains. Heterozygotes have the two parental bands.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000017003 Ensembl Gene Model | MGI Sequence Detail 2233 C57BL/6J ±  kb
transcript ENSMUST00000017147 Ensembl | MGI Sequence Detail 1191 Not Applicable  
polypeptide ENSMUSP00000017147 Ensembl | MGI Sequence Detail 265 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-14661, MGD-MRK-14665, MGI:1924693, MGI:2139432, MGI:98451
References
more
  • Summaries
    All 25
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:7206 Moutier R, et al., Syp-3, a third polymorphic locus for mouse seminal vesicle proteins. Biochem Genet. 1983 Aug;21(7-8):797-800
  • Latest
    J:291572 Shindo M, et al., Deletion of a Seminal Gene Cluster Reinforces a Crucial Role of SVS2 in Male Fertility. Int J Mol Sci. 2019 Sep 14;20(18):4557
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory