About   Help   FAQ
Krt81 Gene Detail
Summary
  • Symbol
    Krt81
  • Name
    keratin 81
  • Synonyms
    Krt2-19
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928858
    NCBI Gene: 64818
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:101356942-101361632 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.90 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    196 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928858
 protein coding gene Chr15:101356942-101361646 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022374
 protein coding gene Chr15:103527471-103531822 (-)
A/J MGP_AJ_G0022336
 protein coding gene Chr15:99427886-99432590 (-)
AKR/J MGP_AKRJ_G0022312
 protein coding gene Chr15:102457058-102462163 (-)
BALB/cJ MGP_BALBcJ_G0022340
 protein coding gene Chr15:99532008-99537434 (-)
C3H/HeJ MGP_C3HHeJ_G0022109
 protein coding gene Chr15:102541820-102549278 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022788
 protein coding gene Chr15:107385868-107392294 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020313
 protein coding gene Chr15:95155847-95160580 (-)
CAST/EiJ MGP_CASTEiJ_G0021635
 protein coding gene Chr15:103413823-103420886 (-)
CBA/J MGP_CBAJ_G0022079
 protein coding gene Chr15:111107309-111115305 (-)
DBA/2J MGP_DBA2J_G0022206
 protein coding gene Chr15:98762621-98767987 (-)
FVB/NJ MGP_FVBNJ_G0022185
 protein coding gene Chr15:97813933-97821019 (-)
LP/J MGP_LPJ_G0022277
 protein coding gene Chr15:103668067-103675652 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022206
 protein coding gene Chr15:114780348-114786224 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022802
 protein coding gene Chr15:102496022-102500267 (-)
PWK/PhJ MGP_PWKPhJ_G0021374
 protein coding gene Chr15:98921775-98930085 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021206
 protein coding gene Chr15:102385610-102393054 (-)
WSB/EiJ MGP_WSBEiJ_G0021684
 protein coding gene Chr15:103127329-103136297 (-)



Homology
more
  • Human Ortholog
    KRT81, keratin 81
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRT81, keratin 81
  • Synonyms
    ghHkb1, Hb-1, HB1, hHAKB2-1, K81, KRTHB1, MLN137
  • Links
    NCBI Gene ID: 3887
    neXtProt AC: NX_Q14533
    UniProt: Q14533

  • Chr Location
    12q13.13; chr12:52285913-52308624 (-)  GRCh38
Human Diseases
more
  • Diseases
    4 with human KRT81,KRT83,KRT86 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    30 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    3
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067615 Ensembl Gene Model | MGI Sequence Detail 4691 C57BL/6J ±  kb
transcript ENSMUST00000061185 Ensembl | MGI Sequence Detail 1843 Not Applicable  
polypeptide ENSMUSP00000056525 Ensembl | MGI Sequence Detail 481 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR018039 Intermediate filament protein, conserved site
    IPR039008 Intermediate filament, rod domain
    IPR003054 Keratin, type II
    IPR032444 Keratin type II head
  • GlyGen
    Q9ERE2 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 12
    Genomic 9
    cDNA 3

    Microarray probesets 4
Other
Accession IDs
less
MGI:2145922
References
more
  • Summaries
    All 48
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 2
    Phenotypes 30
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory