About   Help   FAQ
Sectm1b Gene Detail
Summary
  • Symbol
    Sectm1b
  • Name
    secreted and transmembrane 1B
  • Synonyms
    1810003C24Rik, K12, Sectm1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929083
    NCBI Gene: 58210
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:120944284-120954395 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 84.87 cM, cytoband E2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    404 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929083
 protein coding gene Chr11:120944248-120954395 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019536
 protein coding gene Chr11:125583549-125594193 (-)
A/J MGP_AJ_G0019503
 protein coding gene Chr11:119976308-119986480 (-)
AKR/J MGP_AKRJ_G0019473
 protein coding gene Chr11:123601571-123613442 (-)
BALB/cJ MGP_BALBcJ_G0019478
 protein coding gene Chr11:120345922-120356213 (-)
C3H/HeJ MGP_C3HHeJ_G0019284
 protein coding gene Chr11:123930176-123941515 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019927
 protein coding gene Chr11:129385795-129395561 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017552
 protein coding gene Chr11:116958956-116969322 (-)
CAST/EiJ MGP_CASTEiJ_G0018838
 protein coding gene Chr11:125433049-125442944 (-)
CBA/J MGP_CBAJ_G0019255
 protein coding gene Chr11:134419394-134429479 (-)
DBA/2J MGP_DBA2J_G0019368
 protein coding gene Chr11:119345119-119355260 (-)
FVB/NJ MGP_FVBNJ_G0019359
 protein coding gene Chr11:119062970-119072584 (-)
LP/J MGP_LPJ_G0019439
 protein coding gene Chr11:125864057-125873765 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019392
 protein coding gene Chr11:133236236-133246083 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019966
 protein coding gene Chr11:124282926-124294858 (-)
PWK/PhJ MGP_PWKPhJ_G0018604
 protein coding gene Chr11:120785240-120795366 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018396
 protein coding gene Chr11:124040612-124050516 (-)
WSB/EiJ MGP_WSBEiJ_G0018891
 protein coding gene Chr11:124259155-124269985 (-)



Homology
more
  • Human Ortholog
    SECTM1, secreted and transmembrane 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SECTM1, secreted and transmembrane 1
  • Synonyms
    K12, SECTM
  • Links
    NCBI Gene ID: 6398
    neXtProt AC: NX_Q8WVN6
    UniProt: Q8WVN6

  • Chr Location
    17q25.3; chr17:82321024-82334074 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    39
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039364 Ensembl Gene Model | MGI Sequence Detail 10112 C57BL/6J ±  kb
transcript ENSMUST00000039309 Ensembl | MGI Sequence Detail 2287 Not Applicable  
polypeptide ENSMUSP00000045748 Ensembl | MGI Sequence Detail 212 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 39
    cDNA 39

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916257
References
more
  • Summaries
    All 33
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:64943 Lyman SD, et al., Identification of CD7 as a cognate of the human K12 (SECTM1) protein. J Biol Chem. 2000 Feb 4;275(5):3431-7
  • Latest
    J:301504 Mu X, et al., Identification of a Novel Antisepsis Pathway: Sectm1a Enhances Macrophage Phagocytosis of Bacteria through Activating GITR. J Immunol. 2020 Sep 15;205(6):1633-1643
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory