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Arl6ip4 Gene Detail
Summary
  • Symbol
    Arl6ip4
  • Name
    ADP-ribosylation factor-like 6 interacting protein 4
  • Synonyms
    Aip-4, Srp25
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929500
    NCBI Gene: 65105
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:124254171-124256258 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 63.39 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    96 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929500
 protein coding gene Chr5:124254152-124256259 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030089
 protein coding gene Chr5:127904294-127906401 (+)
A/J MGP_AJ_G0030054
 protein coding gene Chr5:122583183-122585290 (+)
AKR/J MGP_AKRJ_G0029990
 protein coding gene Chr5:126529722-126531829 (+)
BALB/cJ MGP_BALBcJ_G0030065
 protein coding gene Chr5:123918976-123921083 (+)
C3H/HeJ MGP_C3HHeJ_G0029782
 protein coding gene Chr5:127147567-127149674 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030518
 protein coding gene Chr5:132862294-132864401 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027744
 protein coding gene Chr5:117118748-117120868 (+)
CAST/EiJ MGP_CASTEiJ_G0029192
 protein coding gene Chr5:126260002-126262109 (+)
CBA/J MGP_CBAJ_G0029752
 protein coding gene Chr5:138095056-138097163 (+)
DBA/2J MGP_DBA2J_G0029902
 protein coding gene Chr5:122605826-122607933 (+)
FVB/NJ MGP_FVBNJ_G0029858
 protein coding gene Chr5:121637857-121639964 (+)
LP/J MGP_LPJ_G0029991
 protein coding gene Chr5:128453077-128455184 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029889
 protein coding gene Chr5:141675308-141677415 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030559
 protein coding gene Chr5:126152091-126154198 (+)
PWK/PhJ MGP_PWKPhJ_G0028905
 protein coding gene Chr5:121418029-121420136 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028742
 protein coding gene Chr5:123797172-123799278 (+)
WSB/EiJ MGP_WSBEiJ_G0029266
 protein coding gene Chr5:126824145-126826251 (+)



Homology
more
  • Human Ortholog
    ARL6IP4, ARF like GTPase 6 interacting protein 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARL6IP4, ARF like GTPase 6 interacting protein 4
  • Synonyms
    SFRS20, SR-25, SRp25, SRrp37
  • Links
    NCBI Gene ID: 51329
    neXtProt AC: NX_Q66PJ3
    UniProt: Q66PJ3

  • Chr Location
    12q24.31; chr12:122980060-122982913 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    3
  • cDNA Data
    79
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 65105 NCBI Gene Model | MGI Sequence Detail 2088 C57BL/6J ±  kb
transcript NM_144509 RefSeq | MGI Sequence Detail 1182 C57BL/6  
polypeptide Q9JM93 UniProt | EBI | MGI Sequence Detail 229 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000004292 ADP-ribosylation factor-like protein 6-interacting protein 4
    (term hierarchy)
  • InterPro Domains
    IPR019532 Nuclear RNA-splicing-associated protein, SR-25
Molecular
Reagents
less
  • All nucleic 81
    cDNA 79
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2140732, MGI:2140735
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory