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Zfp24 Gene Detail
Summary
  • Symbol
    Zfp24
  • Name
    zinc finger protein 24
  • Synonyms
    3526401F17Rik, 5033419P20Rik, KOX17, ZF-12, Zfp191
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929704
    NCBI Gene: 59057
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:24142759-24153867 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 12.55 cM, cytoband B1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    372 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929704
 protein coding gene Chr18:24142759-24155294 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024197
 protein coding gene Chr18:21723727-21734835 (-)
A/J MGP_AJ_G0024162
 protein coding gene Chr18:21140225-21151343 (-)
AKR/J MGP_AKRJ_G0024131
 protein coding gene Chr18:21783458-21795837 (-)
BALB/cJ MGP_BALBcJ_G0024162
 protein coding gene Chr18:21186248-21197356 (-)
C3H/HeJ MGP_C3HHeJ_G0023930
 protein coding gene Chr18:21716172-21727290 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024604
 protein coding gene Chr18:22659442-22670550 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022046
 protein coding gene Chr18:21011229-21022520 (-)
CAST/EiJ MGP_CASTEiJ_G0023404
 protein coding gene Chr18:21488999-21500324 (-)
CBA/J MGP_CBAJ_G0023898
 protein coding gene Chr18:23261977-23273117 (-)
DBA/2J MGP_DBA2J_G0024030
 protein coding gene Chr18:20814901-20828218 (-)
FVB/NJ MGP_FVBNJ_G0023996
 protein coding gene Chr18:20571129-20582237 (-)
LP/J MGP_LPJ_G0024111
 protein coding gene Chr18:21897400-21908508 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024024
 protein coding gene Chr18:24290303-24301411 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024652
 protein coding gene Chr18:21537660-21548778 (-)
PWK/PhJ MGP_PWKPhJ_G0023148
 protein coding gene Chr18:20948249-20959671 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022957
 protein coding gene Chr18:21766269-21782712 (-)
WSB/EiJ MGP_WSBEiJ_G0023468
 protein coding gene Chr18:21433529-21446018 (-)



Homology
more
  • Human Ortholog
    ZNF24, zinc finger protein 24
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF24, zinc finger protein 24
  • Synonyms
    KOX17, RSG-A, Zfp191, ZNF191, ZSCAN3
  • Links
    NCBI Gene ID: 7572
    neXtProt AC: NX_P17028
    UniProt: P17028

  • Chr Location
    18q12.2; chr18:35332227-35345482 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 5 alleles in 6 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous null for one mutation have hypomyelination of the central nervous system, tremors, tonic seizures and premature death, whereas mice homozygous null for another mutation are embryonic lethal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1138
  • Tissues
    322
  • cDNA Data
    21
  • Literature Summary
    10
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000051469 Ensembl Gene Model | MGI Sequence Detail 11109 C57BL/6J ±  kb
    transcript ENSMUST00000066497 Ensembl | MGI Sequence Detail 5732 Not Applicable  
    polypeptide ENSMUSP00000064637 Ensembl | MGI Sequence Detail 368 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 25
      cDNA 22
      Primer pair 3

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1918016, MGI:1923242, MGI:2147238, MGI:2147248, MGI:2147290
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 10
      Gene Ontology 6
      Phenotypes 13
    • Earliest
      J:66304 Prost JF, et al., Isolation, cloning, and expression of a new murine zinc finger encoding gene. Biochim Biophys Acta. 1999 Oct 28;1447(2-3):278-83
    • Latest
      J:339773 Kim JY, et al., Zinc finger protein 24-dependent transcription factor SOX9 up-regulation protects tubular epithelial cells during acute kidney injury. Kidney Int. 2023 Jun;103(6):1093-1104
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory