Cep295nl MGI Mouse Gene Detail - MGI:1929713

Symbol

Cep295nl
Name

CEP295 N-terminal like
Synonyms

BC100451, Ddc8

Feature Type

protein coding gene
IDs

MGI:1929713
NCBI Gene: 58251
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr11:118223186-118233368 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 83.09 cM, cytoband E2
Mapping Data

1 experiment

SNPs within 2kb

300 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1929713	protein coding gene	Chr11:118223186-118233382 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0019465	protein coding gene	Chr11:122656983-122667897 (-)
A/J	MGP_AJ_G0019433	protein coding gene	Chr11:117219066-117229088 (-)
AKR/J	MGP_AKRJ_G0019403	protein coding gene	Chr11:120777945-120787769 (-)
BALB/cJ	MGP_BALBcJ_G0019408	protein coding gene	Chr11:117580386-117590278 (-)
C3H/HeJ	MGP_C3HHeJ_G0019214	protein coding gene	Chr11:121078766-121088682 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0019857	protein coding gene	Chr11:126413635-126428569 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017482	protein coding gene	Chr11:114222739-114232172 (-)
CAST/EiJ	MGP_CASTEiJ_G0018768	protein coding gene	Chr11:122503654-122513462 (-)
CBA/J	MGP_CBAJ_G0019185	protein coding gene	Chr11:131332028-131341802 (-)
DBA/2J	MGP_DBA2J_G0019297	protein coding gene	Chr11:116604740-116614684 (-)
FVB/NJ	MGP_FVBNJ_G0019289	protein coding gene	Chr11:116245187-116255857 (-)
LP/J	MGP_LPJ_G0019367	protein coding gene	Chr11:122967548-122981577 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019322	protein coding gene	Chr11:130309407-130319137 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019896	protein coding gene	Chr11:121438475-121448339 (-)
PWK/PhJ	MGP_PWKPhJ_G0018534	protein coding gene	Chr11:117976694-117986651 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0018326	protein coding gene	Chr11:121161781-121171078 (-)
WSB/EiJ	MGP_WSBEiJ_G0018820	protein coding gene	Chr11:121389544-121399374 (-)

Human Ortholog

CEP295NL, CEP295 N-terminal like

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CEP295NL, CEP295 N-terminal like
Synonyms

DDC8, KIAA1731NL
Links

HGNC:44659

NCBI Gene ID: 100653515

neXtProt AC: NX_Q96MC4

UniProt: Q96MC4
Chr Location

17q25.3; chr17:78890579-78903217 (-) GRCh38

MGI Vertebrate Homology

Cep295nl stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: CEP295NL
Gene Tree

Cep295nl

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
7 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

6
Endonuclease-mediated

2
Targeted

4
Incidental Mutations

APF , CvDC
Find Mice (IMSR)

21 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

6
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

786
Tissues

47
cDNA Data

12
Literature Summary

2

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

38
RefSeq

6
UniProt

2
CCDS

CCDS25700.1

Ensembl

ENSMUSG00000076433 (Evidence)
NCBI Gene

58251

			Length	Strain/Species	Flank
genomic	58251	NCBI Gene Model \| MGI Sequence Detail	10183	C57BL/6J	± kb
transcript	NM_021440	RefSeq \| MGI Sequence Detail	1993	C57BL/6
polypeptide	Q497N6	UniProt \| EBI \| MGI Sequence Detail	533	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000060022 CEP295 N-terminal-like protein

(term hierarchy)

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All nucleic 15

cDNA 12

Primer pair 3

Microarray probesets 3

Summaries

All 29

Developmental Gene Expression 2

Gene Ontology 2

Phenotypes 7
Earliest

J:66298 Catalano RD, et al., Differential display to identify and isolate novel genes expressed during spermatogenesis. Mol Hum Reprod. 1997 Mar;3(3):215-21
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Cep295nl:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr112125	Chr11:118233349-118233395 (-)	-4 bp
Tssr112124	Chr11:118231440-118231468 (-)	1,914 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24