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Rhox4b Gene Detail
Summary
  • Symbol
    Rhox4b
  • Name
    reproductive homeobox 4B
  • Synonyms
    5430432L21Rik, Ehox, Rhox4.2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930129
    NCBI Gene: 57737
  • Member of
    Rhox cluster, Rhox4 cluster
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    ChrX:36614147-36618931 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 21.73 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    41 from dbSNP Build 142
  • Strain Annotations
    5
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1930129
 protein coding gene ChrX:36614147-36618932 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0035624
 protein coding gene ChrX:32547464-32579513 (+)
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0036145
 protein coding gene ChrX:32877794-32880966 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0036167
 protein coding gene ChrX:32521156-32522939 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0034753
 protein coding gene ChrX:31992458-31993785 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    801
  • Tissues
    70
  • cDNA Data
    4
  • Literature Summary
    13
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 57737 NCBI Gene Model | MGI Sequence Detail 4785 C57BL/6J ±  kb
transcript NM_021300 RefSeq | MGI Sequence Detail 886 C57BL/6  
polypeptide NP_067275 RefSeq | MGI Sequence Detail 205 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001356 Homeobox domain
    IPR009057 Homeobox-like domain superfamily
Molecular
Reagents
less
  • All nucleic 8
    cDNA 6
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1918679
References
more
  • Summaries
    All 34
    Developmental Gene Expression 13
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:307822 Beal R, et al., ARHGEF18/p114RhoGEF Coordinates PKA/CREB Signaling and Actomyosin Remodeling to Promote Trophoblast Cell-Cell Fusion During Placenta Morphogenesis. Front Cell Dev Biol. 2021;9:658006
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory