About   Help   FAQ
Tnfrsf22 Gene Detail
Summary
  • Symbol
    Tnfrsf22
  • Name
    tumor necrosis factor receptor superfamily, member 22
  • Synonyms
    2810028K06Rik, C130035G06Rik, mDcTrailr2, SOBa, Tnfrh2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930270
    NCBI Gene: 79202
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:143188543-143203398 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 88.27 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    468 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1930270
 protein coding gene Chr7:143188540-143203412 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033279
 protein coding gene Chr7:148964472-149011756 (-)
A/J MGP_AJ_G0033261
 protein coding gene Chr7:144621882-144676615 (-)
AKR/J MGP_AKRJ_G0033193
 protein coding gene Chr7:148683597-148712481 (-)
BALB/cJ MGP_BALBcJ_G0033261
 protein coding gene Chr7:144410168-144451174 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0033771
 protein coding gene Chr7:154314250-154337935 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030744
 protein coding gene Chr7:145837373-145850400 (-)
CAST/EiJ MGP_CASTEiJ_G0032299
 protein coding gene Chr7:140765844-140833499 (-)
CBA/J MGP_CBAJ_G0032948
 protein coding gene Chr7:159618881-159647784 (-)
DBA/2J MGP_DBA2J_G0033102
 protein coding gene Chr7:142609924-142626162 (-)
FVB/NJ MGP_FVBNJ_G0033050
 protein coding gene Chr7:142544735-142601506 (-)
LP/J MGP_LPJ_G0033194
 protein coding gene Chr7:150468737-150504694 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033084
 protein coding gene Chr7:160167036-160183050 (-)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0032009
 protein coding gene Chr7:135914474-135927418 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0032411
 protein coding gene Chr7:148648482-148663769 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    734
  • Tissues
    24
  • cDNA Data
    18
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000010751 Ensembl Gene Model | MGI Sequence Detail 14856 C57BL/6J ±  kb
transcript ENSMUST00000075588 Ensembl | MGI Sequence Detail 4170 Not Applicable  
polypeptide ENSMUSP00000075018 Ensembl | MGI Sequence Detail 198 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 18
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
less
MGI:1919925, MGI:2442527
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:65815 Engemann S, et al., Sequence and functional comparison in the beckwith-wiedemann region: implications for a novel imprinting centre and extended imprinting. Hum Mol Genet. 2000 Nov 1;9(18):2691-706
  • Latest
    J:277990 Uysal H, et al., Transmembrane TNF and Partially TNFR1 Regulate TNFR2 Expression and Control Inflammation in Mycobacterial-Induced Pleurisy. Int J Mol Sci. 2018 Jul 4;19(7):1959
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory