Hgh1 Gene Detail

Summary

• Symbol
  Hgh1
• Name
  HGH1 cochaparone
• Synonyms
  Brp16, D15Ertd741e, Fam203a

• Feature Type
  protein coding gene
• IDs
  MGI:1930628
  NCBI Gene: 59053
• Alliance
  genome feature page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr15:76253098-76255637 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 15, 35.78 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  147 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1930628	protein coding gene	Chr15:76253064-76256056 (+)
129S1/SvImJ	ENSMUSG00200050476	protein coding gene	Chr15:73367294-73369833 (+)
A/J	ENSMUSG00195050277	protein coding gene	Chr15:73341765-73344305 (+)
AKR/J	ENSMUSG00220047521	protein coding gene	Chr15:73352774-73355313 (+)
BALB/cJ	ENSMUSG00180051602	protein coding gene	Chr15:73166913-73169453 (+)
C3H/HeJ	ENSMUSG00175051808	protein coding gene	Chr15:73530337-73532876 (+)
C57BL/6NJ	ENSMUSG00215048129	protein coding gene	Chr15:73259125-73261663 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019925	protein coding gene	Chr15:70317014-70319510 (+)
CAST/EiJ	ENSTCUG00005040033	protein coding gene	Chr15:72872369-72874897 (+)
CBA/J	ENSMUSG00210037101	protein coding gene	Chr15:73305577-73308116 (+)
DBA/2J	ENSMUSG00185048415	protein coding gene	Chr15:73282736-73285275 (+)
FVB/NJ	ENSMUSG00205049329	protein coding gene	Chr15:73035028-73037567 (+)
JF1/MsJ	ENSUMUG00000051515	protein coding gene	Chr15:72933439-72935977 (+)
LP/J	ENSMUSG00230052464	protein coding gene	Chr15:76648268-76650807 (+)
NOD/ShiLtJ	ENSMUSG00190051859	protein coding gene	Chr15:73287617-73290157 (+)
NZO/HlLtJ	ENSMUSG00225050099	protein coding gene	Chr15:76952778-76955318 (+)
PWK/PhJ	ENSLUMG00010047730	protein coding gene	Chr15:73225367-73227896 (+)
SPRET/EiJ	ENSMSPG00010043759	protein coding gene	Chr15:74831108-74834518 (+)
WSB/EiJ	ENSIUOG00005036392	protein coding gene	Chr15:73345561-73348101 (+)

Homology

• Human Ortholog
  HGH1, HGH1 cochaperone

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  HGH1, HGH1 cochaperone
  
• Synonyms
  BRP16, BRP16L, C8orf30A, C8orf30B, FAM203A, FAM203B
• Links
  HGNC:24161

  NCBI Gene ID: 51236

  UniProt: Q9BTY7

  
  
• Chr Location
  8q24.3; chr8:144137774-144140851 (+)  GRCh38

---

• MGI Vertebrate Homology
  Hgh1 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: HGH1
• Gene Tree
  Hgh1
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  29 phenotype references
  

• All Mutations and Alleles
  9
• Chemically induced (other)
  3
• Gene trapped
  2
• Radiation induced
  2
• Targeted
  2
• Genomic Mutations
  5 involving Hgh1
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  9 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  2

Expression

• Assay Results
  640
• Tissues
  29
• cDNA Data
  32
• Literature Summary
  2

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase hgh1
  ZFIN hgh1

Sequences &
Gene Models

• All Sequences
  48
• RefSeq
  6
• UniProt
  1
• CCDS
  CCDS27569.1

• Ensembl
  ENSMUSG00000022554 (Evidence)
• NCBI Gene
  59053

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000022554	Ensembl Gene Model | MGI Sequence Detail	2540	C57BL/6J
transcript	ENSMUST00000023213	Ensembl | MGI Sequence Detail	1993	Not Applicable
polypeptide	ENSMUSP00000023213	Ensembl | MGI Sequence Detail	393	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000004819 co-chaperone protein HGH1 homolog
  (term hierarchy)
• InterPro Domains
  IPR011989 Armadillo-like helical
  IPR016024 Armadillo-type fold
  IPR039717 Protein Hgh1
  IPR007206 Protein HGH1 C-terminal
  IPR007205 Protein HGH1 N-terminal

Molecular
Reagents

• All nucleic 33

  cDNA 32

  Primer pair 1

  
  

  Microarray probesets 3

Other
Accession IDs

MGI:1289236

References

• Summaries
  All 56

  Developmental Gene Expression 2

  Diseases 1

  Gene Ontology 2

  Phenotypes 29
• Earliest
  J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
• Latest
  J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)

TSS for Hgh1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr131788	Chr15:76253084-76253136 (+)	12 bp