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Zfp386 Gene Detail
Summary
  • Symbol
    Zfp386
  • Name
    zinc finger protein 386 (Kruppel-like)
  • Feature Type
    protein coding gene
  • IDs
    MGI:1930708
    NCBI Gene: 56220
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:116011334-116026851 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 12, 62.59 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    612 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1930708
protein coding gene Chr12:116011334-116026980 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020178
protein coding gene Chr12:118896072-118913137 (+)
A/J MGP_AJ_G0020134
protein coding gene Chr12:114561858-114577606 (+)
AKR/J MGP_AKRJ_G0020109
protein coding gene Chr12:118034217-118049807 (+)
BALB/cJ MGP_BALBcJ_G0020117
protein coding gene Chr12:114976304-114992200 (+)
C3H/HeJ MGP_C3HHeJ_G0019921
protein coding gene Chr12:118290437-118306278 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020564
protein coding gene Chr12:122655793-122671429 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018176
protein coding gene Chr12:110253794-110269617 (+)
CAST/EiJ MGP_CASTEiJ_G0019461
protein coding gene Chr12:112140977-112156606 (+)
CBA/J MGP_CBAJ_G0019888
protein coding gene Chr12:127528375-127544200 (+)
DBA/2J MGP_DBA2J_G0020005
protein coding gene Chr12:113925167-113938065 (+)
FVB/NJ MGP_FVBNJ_G0019990
protein coding gene Chr12:112609383-112624997 (+)
LP/J MGP_LPJ_G0020079
protein coding gene Chr12:118937907-118953537 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020026
protein coding gene Chr12:130836018-130851667 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020593
protein coding gene Chr12:117208591-117224178 (+)
PWK/PhJ MGP_PWKPhJ_G0019223
protein coding gene Chr12:108666223-108681873 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019028
protein coding gene Chr12:110123223-110138964 (+)
WSB/EiJ MGP_WSBEiJ_G0019519
protein coding gene Chr12:118155553-118168454 (+)



Homology
more
  • Human Ortholog
    ZNF519, zinc finger protein 519
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF519, zinc finger protein 519
  • Synonyms
    HsT2362
  • Links
    NCBI Gene ID: 162655
    neXtProt AC: NX_Q8TB69
    UniProt: Q8TB69

  • Chr Location
    18p11.21; chr18:14057457-14132490 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56220 NCBI Gene Model | MGI Sequence Detail 15518 C57BL/6J ±  kb
transcript NM_001004066 RefSeq | MGI Sequence Detail 4680 C57BL/6  
polypeptide NP_001004066 RefSeq | MGI Sequence Detail 626 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 63
    cDNA 62
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 31
    Developmental Gene Expression 6
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory