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Or8a1b Gene Detail
Summary
  • Symbol
    Or8a1b
  • Name
    olfactory receptor family 8 subfamily A member 1B
  • Synonyms
    GA_x6K02T2PVTD-31389446-31388517, M72, MOR171-3, MOR171-3, Olfr160
  • Feature Type
    protein coding gene
  • IDs
    MGI:1931271
    NCBI Gene: 80706
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr9:37622644-37623576 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 20.80 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    156 from dbSNP Build 142
  • Strain Annotations
    8
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1931271
 protein coding gene Chr9:37620260-37627546 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J MGP_AKRJ_G0034479
 protein coding gene Chr9:35526028-35527064 (-)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0035065
 protein coding gene Chr9:36859578-36873492 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031991
 protein coding gene Chr9:33856107-33857123 (-)
CAST/EiJ MGP_CASTEiJ_G0033577
 protein coding gene Chr9:35655717-35661663 (-)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0034328
 protein coding gene Chr9:34065644-34066900 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0034374
 protein coding gene Chr9:39726904-39743370 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0033117
 protein coding gene Chr9:35667237-35676543 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    OR8A1, olfactory receptor family 8 subfamily A member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OR8A1, olfactory receptor family 8 subfamily A member 1
  • Synonyms
    OR11-318, OST025
  • Links
    NCBI Gene ID: 390275
    neXtProt AC: NX_Q8NGG7
    UniProt: Q8NGG7

  • Chr Location
    11q24.2
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 3 alleles in 3 genetic backgrounds
    14 phenotypes from multigenic genotypes
    1 images
    53 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a reporter allele respond heterogeneously to odorants and display abnormal innervation of glomeruli by olfactory sensory axons in the olfactory bulb.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    717
  • Tissues
    5
  • cDNA Data
    2
  • Literature Summary
    13
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 80706 NCBI Gene Model | MGI Sequence Detail 933 C57BL/6J ±  kb
transcript NM_030553 RefSeq | MGI Sequence Detail 933 C57BL/6  
polypeptide NP_085030 RefSeq | MGI Sequence Detail 309 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR017452 GPCR, rhodopsin-like, 7TM
    IPR000276 G protein-coupled receptor, rhodopsin-like
    IPR000725 Olfactory receptor
Molecular
Reagents
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  • All nucleic 5
    cDNA 3
    Primer pair 1
    Other 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:7276814
References
more
  • Summaries
    All 78
    Developmental Gene Expression 13
    Gene Ontology 3
    Phenotypes 53
  • Earliest
    J:67661 Zheng C, et al., Peripheral olfactory projections are differentially affected in mice deficient in a cyclic nucleotide-gated channel subunit. Neuron. 2000 Apr;26(1):81-91
  • Latest
    J:347599 Raja R, et al., Insertion of a neomycin selection cassette in the Amigo1 locus alters gene expression in the olfactory epithelium leading to region-specific defects in olfactory receptor neuron development. Genesis. 2024 Apr;62(2):e23594
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory