pogo Gene Detail

Summary

• Symbol
  pogo
• Name
  pogostick

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:1932969
  NCBI Gene: 117223
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 8, Syntenic
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotypes from 1 allele in 1 genetic background
  1 images
  9 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  0 strains or lines available

Homozygous spontaneous mutants show a progressive ataxia characterized by a wobbly gait, a tendency to fall over and impaired interlimb coordination, and display altered Purkinje cell dendrite morphology, loss of Purkinje cells in the vermis, and reducedglutamate concentrations in the cerebellum.

Sequences &
Gene Models

• NCBI Gene
  117223

References

• Summaries
  All 10

  Phenotypes 9
• Earliest
  J:67170 Jeong Y, et al., Abnormalities in cerebellar Purkinje cells in the novel ataxic mutant mouse, pogo. Brain Res Dev Brain Res. 2000 Dec 29;125(1-2):61-7
• Latest
  J:177326 Lee KY, et al., Altered Purkinje cell responses and calmodulin expression in the spontaneously ataxic mouse, Pogo. Eur J Neurosci. 2011 Apr;33(8):1493-503